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Pharmacology Research Articles

Activation of the serotonin 5-HT3 receptor in the dorsal raphe nucleus suppresses REM sleep in the rat
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Treatment with haloperidol and diazepam alters GABAA receptor density in the rat brain
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Placebo and modafinil effect on sleepiness in obstructive sleep apnea
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Platelet serotonin concentration and suicidal behavior in combat related posttraumatic stress disorder
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Investigating the neuropsychological and neuroanatomical changes that occur over the first 2–3 years of illness in patients with first-episode schizophrenia
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Hallucinatory disorder, an original clinical picture? Clinical and imaging data
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Δ9-Tetrahydrocannabinol-induced cognitive deficits are reversed by olanzapine but not haloperidol in rats
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A multilevel analysis of the influence of Apolipoprotein E genotypes on depressive symptoms in late-life moderated by the environment
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Fluoxetine versus sertraline in the treatment of patients with undifferentiated somatoform disorder: A randomized, open-label, 12-week, parallel-group trial
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Stereotypic behaviour in the deer mouse: Pharmacological validation and relevance for obsessive compulsive disorder
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Hypothalamic–pituitary–adrenal axis activity, dehydroepiandrosterone sulphate and their relationships with aggression in early and late alcohol withdrawal
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A relationship between bipolar II disorder and borderline personality disorder?
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Memantine decreases hippocampal glutamate levels: A magnetic resonance spectroscopy study
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Associations between increases in plasma n-3 polyunsaturated fatty acids following supplementation and decreases in anger and anxiety in substance abusers
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Defining mixed depression
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High field 1H MRS of the hippocampus after donepezil treatment in Alzheimer disease
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Neural correlates of affective processing in response to sad and angry facial stimuli in patients with major depressive disorder
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Nuclei-and condition-specific responses to pain in the bed nucleus of the stria terminalis
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Cognitive functioning related to quality of life in schizophrenia
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Lithium effects on brain glutamatergic and GABAergic systems of healthy volunteers as measured by proton magnetic resonance spectroscopy
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Can serotonin transporter genotype predict serotonergic function, chronicity, and severity of drinking?
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Modulation of defensive responses and anxiety-like behaviors by group I metabotropic glutamate receptors located in the dorsolateral periaqueductal gray
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Abnormal prediction error is associated with negative and depressive symptoms in schizophrenia
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Distinct behavioral and neurochemical alterations induced by intermittent hypoxia or paradoxical sleep deprivation in rats
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Calcium channel antagonists suppress cross-tolerance to the anxiogenic effects of d-amphetamine and nicotine in the mouse elevated plus maze test
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The safety and effects of the beta-blocker, nadolol, in mild asthma: An open-label pilot study
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Evaluation of fatty acid amides in the carrageenan-induced paw edema model
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Role of the cyclic-AMP/PKA cascade and of P/Q-type Ca++ channels in endocannabinoid-mediated long-term depression in the nucleus accumbens
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Neurotensin reduces glutamatergic transmission in the dorsolateral striatum via retrograde endocannabinoid signaling
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Cannabinoid receptor-mediated translocation of NO-sensitive guanylyl cyclase and production of cyclic GMP in neuronal cells
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The stimulatory effect of phosphatidylethanolamine on N-acylphosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-PLD)
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Roflumilast attenuates pulmonary inflammation upon segmental endotoxin challenge in healthy subjects: A randomized placebo-controlled trial
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The role of Pneumococcal vaccine
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Denufosol: A review of studies with inhaled P2Y2 agonists that led to Phase 3
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Biodistribution in mice and severity of damage in rat lungs following pulmonary delivery of 9-nitrocamptothecin liposomes
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Alpha glucocorticoid receptor expression in different experimental rat models of acute lung injury
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Cytokines, bone turnover markers and weight change in candidates for lung transplantation
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Efficacy and safety of a new pressurised metered-dose inhaler formulation of budesonide/formoterol in children with asthma: A superiority and therapeutic equivalence study
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Effects of atomoxetine and methylphenidate on attention and impulsivity in the 5-choice serial reaction time test
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Comparable long-term safety and efficacy of a novel budesonide/formoterol pressurized metered-dose inhaler versus budesonide/formoterol Turbuhaler® in adolescents and adults with asthma
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Pharmacological characterization of 3-azabicyclo[3,2,1] octane-1-yl-l-leucyl-d-tryptophanyl-d-4-Cl-phenylalanine: A novel ETA receptor-selective antagonist
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Toxicity of prolonged high dose inhaled PGE1 in ventilated neonatal pigs
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Phosphodiesterase 4 inhibitors delay human eosinophil and neutrophil apoptosis in the absence and presence of salbutamol
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Inhibition of neutrophil elastase reduces lung injury and bacterial count in hamsters
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A role for MC3R in modulating lung inflammation
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Modulation of high-frequency oscillations associated with NMDA receptor hypofunction in the rodent nucleus accumbens by lamotrigine
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The effect of early maternal separation on brain derived neurotrophic factor and monoamine levels in adult heterozygous reeler mice
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Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice
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Obsessive–compulsive disorder and immunology: A review
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Tobacco/nicotine and endogenous brain opioids
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Calcium/calmodulin-dependent kinase II regulates the interaction between the serotonin transporter and syntaxin 1A
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Non-steroidal anti-inflammatory drugs have potent anti-fibrillogenic and fibril-destabilizing effects for α-synuclein fibrils in vitro
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Amphetamine-induced decreases in dopamine transporter surface expression are protein kinase C-independent
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The role of kinin B1 receptors in the nociception produced by peripheral protein kinase C activation in mice
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Inhibition of morphine-induced amnesia in morphine-sensitized mice: Involvement of dorsal hippocampal GABAergic receptors
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Serotonin depletion in the dorsal and ventral hippocampus: Effects on locomotor hyperactivity, prepulse inhibition and learning and memory
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An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function
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Crosstalk of vascular 5-HT1 receptors with other receptors: Clinical implications
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Fine-tuning serotonin2c receptor function in the brain: Molecular and functional implications
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Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases
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Flavan-3-ol derivatives are positive modulators of GABAA receptors with higher efficacy for the α2 subtype and anxiolytic action in mice
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Activation of ERβ increases levels of phosphorylated nNOS and NO production through a Src/PI3K/Akt-dependent pathway in hypothalamic neurons
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Liver Kupffer cells control the magnitude of the inflammatory response in the injured brain and spinal cord
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5-HT2 receptor-mediated reversal of the inhibition of hippocampal long-term potentiation by acute inescapable stress
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The selective delta opioid agonist SNC80 enhances amphetamine-mediated efflux of dopamine from rat striatum
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Adrenomedullin enhances baroreceptor reflex response via cAMP/PKA signaling in nucleus tractus solitarii of rats
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6-OHDA-induced hemiparkinsonism and chronic l-DOPA treatment increase dopamine D1-stimulated [3H]-GABA release and [3H]-cAMP production in substantia nigra pars reticulata of the rat
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Up-regulation of protein l-isoaspartyl methyltransferase expression by lithium is mediated by glycogen synthase kinase-3 inactivation and β-catenin stabilization
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Ethanol inhibition of kainate receptor-mediated excitatory neurotransmission in the rat basolateral nucleus of the amygdala
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Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice
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Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents
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Neuroprotection by group I mGlu receptors in a rat hippocampal slice model of cerebral ischemia is associated with the PI3K–Akt signaling pathway: A novel postconditioning strategy?
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Functional interaction between adenosine A2A and group III metabotropic glutamate receptors to reduce parkinsonian symptoms in rats
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The novel NTPDase inhibitor sodium polyoxotungstate (POM-1) inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition
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Sustained administration of bupropion alters the neuronal activity of serotonin, norepinephrine but not dopamine neurons in the rat brain
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Ex vivo assessment of binding site occupancy of monoamine reuptake inhibitors: Methodology and biological significance
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Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice
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Diphenyl diselenide exerts anxiolytic-like effect in Wistar rats: Putative roles of GABAA and 5HT receptors
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The role of the CB1 receptor in the regulation of sleep
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Dopamine D1 receptors and group I metabotropic glutamate receptors contribute to the induction of long-term potentiation in the nucleus accumbens
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Modulation of NMDA receptors by intrathecal administration of the sensory neuron-specific receptor agonist BAM8–22
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Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function
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Effects of sulindac sulfide on the membrane architecture and the activity of γ-secretase
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HMJ-53A accelerates slow inactivation gating of voltage-gated K+ channels in mouse neuroblastoma N2A cells
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N-methyl-d-aspartate mechanisms in depolarization of augmenting expiratory neurons during the expulsive phase of fictive cough in decerebrate cats
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Folic acid protects motor neurons against the increased homocysteine, inflammation and apoptosis in SOD1G93A transgenic mice
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5HT2 receptor activation facilitates P2X receptor mediated excitatory neurotransmission to cardiac vagal neurons in the nucleus ambiguus
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The role of NMDA receptors in regulating group II metabotropic glutamate receptor-mediated long-term depression in rat medial prefrontal cortex
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Antipsychotic-induced alterations in CB1 receptor-mediated G-protein signaling and in vivo pharmacology in rats
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Impairment of endocannabinoids activity in the dorsolateral striatum delays extinction of behavior in a procedural memory task in rats
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Effects of subtype-selective group I mGluR antagonists on synchronous activity induced by 4-aminopyridine/CGP 55845 in adult guinea pig hippocampal slices
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The role of RIM1α in BDNF-enhanced glutamate release
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Retigabine reduces the excitability of unmyelinated peripheral human axons
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α-Synuclein expression in the brain and blood during abstinence from chronic alcohol drinking in mice
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Recruitment of β-arrestin2 to the dopamine D2 receptor: Insights into anti-psychotic and anti-parkinsonian drug receptor signaling
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Ischemic stroke and neurogenesis in the subventricular zone
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Regulation of cerebral vasculature in normal and ischemic brain
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Delayed, context- and dopamine D1 receptor-dependent activation of ERK in morphine-sensitized mice
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Removing TRPV1-expressing primary afferent neurons potentiates the spinal analgesic effect of δ-opioid agonists on mechano-nociception
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Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function
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