Endothelin-1 (1–31): From chymase-dependent synthesis to cardiovascular pathologies Fulltext Access 12 Pages 2008
Preconditioning by inhaled nitric oxide prevents hyperoxic and ischemia/reperfusion injury in rat lungs Fulltext Access 12 Pages 2008
Alteration of enzymatic properties of cell-surface antigen CD38 by agonistic anti-CD38 antibodies that prolong B cell survival and induce activation Fulltext Access 12 Pages 2008
Comparison of twice-daily inhaled ciclesonide and fluticasone propionate in patients with moderate-to-severe persistent asthma Fulltext Access 12 Pages 2008
Do airway clearance mechanisms influence the local and systemic effects of inhaled corticosteroids? Fulltext Access 12 Pages 2008
Histamine reverses IL-5-afforded human eosinophil survival by inducing apoptosis: Pharmacological evidence for a novel mechanism of action of histamine Fulltext Access 12 Pages 2008
Macrophage immunomodulatory activity of polysaccharides isolated from Opuntia polyacantha Fulltext Access 12 Pages 2008
Validation of guinea pig model of allergic rhinitis by oral and topical drugs Fulltext Access 12 Pages 2008
The beneficial effect of Rheum tanguticum polysaccharide on protecting against diarrhea, colonic inflammation and ulceration in rats with TNBS-induced colitis: The role of macrophage mannose receptor in inflammation and immune response Fulltext Access 12 Pages 2008
Cyclin-dependent kinase 9: a key transcriptional regulator and potential drug target in oncology, virology and cardiology Fulltext Access 12 Pages 2008
Toxicity studies on dermal application of plant extract of Plumbago zeylanica used in Ethiopian traditional medicine Fulltext Access 13 Pages 2008
Are the available experimental models of type 2 diabetes appropriate for a gender perspective? Fulltext Access 13 Pages 2008
G protein-coupled receptor dimers: Functional consequences, disease states and drug targets Fulltext Access 13 Pages 2008
Ethnomedicines used against four common ailments by the tribal communities of Lahaul-Spiti in western Himalaya Fulltext Access 13 Pages 2008
Mutagenic and antimutagenic properties of extracts from South African traditional medicinal plants Fulltext Access 13 Pages 2008
Artemisia annua as a self-reliant treatment for malaria in developing countries Fulltext Access 13 Pages 2008
Use of and familiarity with dietary supplement information references by practicing pharmacists Fulltext Access 13 Pages 2008
Medication therapy management in pharmacy practice: Core elements of an MTM service model (version 2.0) Fulltext Access 13 Pages 2008
A physiologically based pharmacokinetic (PBPK) model to characterize and predict the disposition of monoclonal antibody CC49 and its single chain Fv constructs Fulltext Access 13 Pages 2008
Induction of high expression of CCR7 and high production of IL-12 in human monocyte-derived dendritic cells by a new bacterial component: LCOS 1013 Fulltext Access 13 Pages 2008
Assessment of the bioequivalence of two formulations of clarithromycin extended-release 500-mg tablets under fasting and fed conditions: A single-dose, randomized, open-label, two-period, two-way crossover study in healthy Jordanian male volunteers Fulltext Access 13 Pages 2008
Long-term persistence with statin treatment in a not-for-profit health maintenance organization: A population-based retrospective cohort study in Israel Fulltext Access 13 Pages 2008
The economics of pediatric formulation development for off-patent drugs Fulltext Access 13 Pages 2008
Stability of doripenem in vitro in representative infusion solutions and infusion bags Fulltext Access 13 Pages 2008
Adenosine 3â²,5â²-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors Fulltext Access 13 Pages 2008
Toxicological effects of cinnabar in rats by NMR-based metabolic profiling of urine and serum Fulltext Access 13 Pages 2008
Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide Fulltext Access 13 Pages 2008
Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: Contribution of DNA replication, transcription inhibition and Chk/p53 signaling Fulltext Access 13 Pages 2008
Central role of mitochondria and p53 in PUVA-induced apoptosis in human keratinocytes cell line NCTC-2544 Fulltext Access 13 Pages 2008
Tumor necrosis factor-α induces MMP-9 expression via p42/p44 MAPK, JNK, and nuclear factor-κB in A549 cells Fulltext Access 13 Pages 2008
Reactive oxygen species-dependent HSP90 protein cleavage participates in arsenical As+ 3- and MMA+ 3-induced apoptosis through inhibition of telomerase activity via JNK activation Fulltext Access 13 Pages 2008
Response of human renal tubular cells to cyclosporine and sirolimus: A toxicogenomic study Fulltext Access 13 Pages 2008
Characterization of biliary conjugates of 4,4′-methylenedianiline in male versus female rats Fulltext Access 13 Pages 2008
Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53 Fulltext Access 13 Pages 2008
Developmental neurotoxicity of Propylthiouracil (PTU) in rats: Relationship between transient hypothyroxinemia during development and long-lasting behavioural and functional changes Fulltext Access 13 Pages 2008
Macrolide antibiotics as immunomodulatory medications: Proposed mechanisms of action Fulltext Access 13 Pages 2008
Respiratory sensitization and allergy: Current research approaches and needs Fulltext Access 13 Pages 2008
Dithiothreitol abrogates the effect of arsenic trioxide on normal rat liver mitochondria and human hepatocellular carcinoma cells Fulltext Access 13 Pages 2008
Toxicogenomic analysis of the hepatic effects of perfluorooctanoic acid on rare minnows (Gobiocypris rarus) Fulltext Access 13 Pages 2008
The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation Fulltext Access 13 Pages 2008
Lipopolysaccharide induces VCAM-1 expression and neutrophil adhesion to human tracheal smooth muscle cells: Involvement of Src/EGFR/PI3-K/Akt pathway Fulltext Access 13 Pages 2008
A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells Fulltext Access 13 Pages 2008
Modulation of neurotransmitter systems by dehydroepiandrosterone and dehydroepiandrosterone sulfate: Mechanism of action and relevance to psychiatric disorders Fulltext Access 13 Pages 2008
Influence of comorbid obsessive-compulsive symptoms on brain event-related potentials in Gilles de la Tourette syndrome Fulltext Access 13 Pages 2008
A systematic review of off-label uses of memantine for psychiatric disorders Fulltext Access 13 Pages 2008
Actin-targeting natural compounds as tools to study the role of actin cytoskeleton in signal transduction Fulltext Access 13 Pages 2008
The A3 adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-κB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats Fulltext Access 13 Pages 2008
Characterisation of the in vitro activity of the depsipeptide histone deacetylase inhibitor spiruchostatin A Fulltext Access 13 Pages 2008
The effects of environmental neurotoxicants on the dopaminergic system: A possible role in drug addiction Fulltext Access 13 Pages 2008
Uncoupling between noradrenergic and serotonergic neurons as a molecular basis of stable changes in behavior induced by repeated drugs of abuse Fulltext Access 13 Pages 2008
The neurobiology and genetics of impulse control disorders: Relationships to drug addictions Fulltext Access 13 Pages 2008
A novel formulation of inhaled doxycycline reduces allergen-induced inflammation, hyperresponsiveness and remodeling by matrix metalloproteinases and cytokines modulation in a mouse model of asthma Fulltext Access 13 Pages 2008
Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: Role in the cell cycle and apoptosis Fulltext Access 13 Pages 2008
Synthesis and pharmacological evaluation of the novel pseudo-symmetrical tamoxifen derivatives as anti-tumor agents Fulltext Access 13 Pages 2008
15-Deoxy-Δ12,14-prostaglandin J2 rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: Potential roles of Akt and ERK1/2 Fulltext Access 13 Pages 2008
Molecular mechanism of L-DNase II activation and function as a molecular switch in apoptosis Fulltext Access 13 Pages 2008
SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IκBα kinase activation Fulltext Access 13 Pages 2008
Inhibition of nitric oxide production by the carbazole compound LCY-2-CHO via blockade of activator protein-1 and CCAAT/enhancer-binding protein activation in microglia Fulltext Access 13 Pages 2008
Structure–activity relationship for adenosine kinase from Mycobacterium tuberculosis: II. Modifications to the ribofuranosyl moiety Fulltext Access 13 Pages 2008
Anti-inflammatory interventions of NF-κB signaling: Potential applications and risks Fulltext Access 13 Pages 2008
Uracil nucleotides: From metabolic intermediates to neuroprotection and neuroinflammation Fulltext Access 13 Pages 2008
Extracts and constituents of Leontopodium alpinum enhance cholinergic transmission: Brain ACh increasing and memory improving properties Fulltext Access 13 Pages 2008
Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the “primer grip” region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants Fulltext Access 13 Pages 2008
A selective blocker of Kv1.2 and Kv1.3 potassium channels from the venom of the scorpion Centruroides suffusus suffusus Fulltext Access 13 Pages 2008
Helioxanthin inhibits interleukin-1β-induced MIP-1β production by reduction of c-jun expression and binding of the c-jun/CREB1 complex to the AP-1/CRE site of the MIP-1β promoter in Huh7 cells Fulltext Access 13 Pages 2008
The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation Fulltext Access 13 Pages 2008
Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI Fulltext Access 13 Pages 2008
Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases Fulltext Access 13 Pages 2008
Heterocyclic organobismuth(III) induces apoptosis of human promyelocytic leukemic cells through activation of caspases and mitochondrial perturbation Fulltext Access 13 Pages 2008
Efficacy and tolerability of salmeterol/fluticasone propionate versus montelukast in childhood asthma: A prospective, randomized, double-blind, double-dummy, parallel-group study Fulltext Access 13 Pages 2008
Efficacy and safety profiles of a new S(—)-amlodipine nicotinate formulation versus racemic amlodipine besylate in adult Korean patients with mild to moderate hypertension: An 8-week, multicenter, randomized, double-blind, double-dummy, parallel-group, ph Fulltext Access 13 Pages 2008
A review of the efficacy of smoking-cessation pharmacotherapies in nonwhite populations Fulltext Access 13 Pages 2008
Role of corticosteroids in the management of acute respiratory distress syndrome Fulltext Access 13 Pages 2008
A 52-Week, Randomized, Open-Label, Parallel-Group Comparison of the Tolerability and Effects of Pitavastatin and Atorvastatin on High-Density Lipoprotein Cholesterol Levels and Glucose Metabolism in Japanese Patients with Elevated Levels of Low-Density Li Fulltext Access 13 Pages 2008
Six-month, prospective, longitudinal, open-Label caffeine and dextromethorphan phenotyping study in children with growth hormone deficiency receiving recombinant human growth hormone replacement Fulltext Access 13 Pages 2008
Use of darbepoetin alfa and epoetin alfa in clinical practice in patients with cancer-related anemia Fulltext Access 13 Pages 2008
Ambulatory blood pressure-lowering effects of valsartan and enalapril after a missed dose in previously untreated patients with hypertension: A prospective, randomized, open-label, blinded end-point trial Fulltext Access 13 Pages 2008
Pharmacokinetic/pharmacodynamic profile of mometasone furoate nasal spray: Potential effects on clinical safety and efficacy Fulltext Access 13 Pages 2008
Cost-effectiveness analysis of rosuvastatin versus atorvastatin, simvastatin, and pravastatin from a Canadian health system perspective Fulltext Access 13 Pages 2008
Risk of discontinuation of risperidone after exposure to potentially interacting drugs: A nested case-control study in patients with schizophrenia Fulltext Access 13 Pages 2008
Impact of corticosteroid-related symptoms in patients with immune thrombocytopenic purpura: Results of a survey of 985 patients Fulltext Access 13 Pages 2008
Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation Fulltext Access 13 Pages 2008
Efficacy and tolerability of exenatide monotherapy over 24 weeks in antidiabetic drug—naive patients with type 2 diabetes: A randomized, double-blind, placebo-controlled, parallel-group study Fulltext Access 13 Pages 2008
Pharmacokinetics, efficacy, and tolerability of fentanyl following intranasal versus intravenous administration in adults undergoing third-molar extraction: A randomized, double-blind, double-dummy, two-way, crossover study Fulltext Access 13 Pages 2008
Perception of Prescription Medicine Sample Packs Among Australian Professional, Government, Industry, and Consumer Organizations, Based on Automated Textual Analysis of One-on-One Interviews Fulltext Access 13 Pages 2008
Adherence to guidelines for use of erythropoiesis-stimulating agents in patients with chemotherapy-induced anemia: Results of a retrospective study of an electronic medical-records database in the United States, 2002–2006 Fulltext Access 13 Pages 2008
Relationship between compliance and persistence with osteoporosis medications and fracture risk in primary health care in France: A retrospective case—control analysis Fulltext Access 13 Pages 2008
Bakuchiol analogs inhibit monoamine transporters and regulate monoaminergic functions Fulltext Access 13 Pages 2008
STI571/doxorubicin concentration-dependent switch for diverse caspase actions in CML cell line K562 Fulltext Access 13 Pages 2008
Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells Fulltext Access 13 Pages 2008
Fluoxetine-induced proliferation and differentiation of neural progenitor cells isolated from rat postnatal cerebellum Fulltext Access 13 Pages 2008
Development of XPA067.06, a potent high affinity human anti-gastrin monoclonal antibody Fulltext Access 13 Pages 2008
α-Galactosylceramide modulates the induction of indoleamine 2,3-dioxygenase in antigen presenting cells Fulltext Access 13 Pages 2008