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Pharmacology Research Articles

Biowaiver monographs for immediate release solid oral dosage forms: Acetaminophen (paracetamol)
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A Novel MDR1 G1199T Variant Alters Drug Resistance and Efflux Transport Activity of P-Glycoprotein in Recombinant Hek Cells
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Kinetic Analyses for Species Differences in P-glycoprotein-Mediated Drug Transport
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Determination of drug plasma protein binding by solid phase microextraction
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Cerebral kinetics of oxycodone in conscious sheep
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Pharmacokinetics of Chlorzoxazone in Rats with Diabetes: Induction of CYP2E1 on 6-Hydroxychlorzoxazone Formation
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In-line Measurement of a Drug Substance via Near Infrared Spectroscopy to Ensure a Robust Crystallization Process
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Factors influencing regional differences in intestinal absorption of UK-343,664 in rat: Possible role in dose-dependent pharmacokinetics
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Dose and airflow dependence of benzyl alcohol disposition on skin
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Effect of pH and ionic strength on the physical stability of adenovirus type 5
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Preparation, characterization, and drug release in vitro of chitosan-glycyrrhetic acid nanoparticles
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Solubilization of two structurally related anticancer drugs: XK-469 and PPA
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Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture
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Hepatic Disposition of the Cytochrome P450 2E1 Marker Chlorzoxazone and its Hydroxylated Metabolite in Isolated Perfused Rat Livers
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Postmortem brain fatty acid profile of levodopa-treated Parkinson disease patients and parkinsonian monkeys
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Muscarinic acetylcholine receptors mediate oligodendrocyte progenitor survival through Src-like tyrosine kinases and PI3K/Akt pathways
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GABAA receptor β isoform protein expression in human alcoholic brain: interaction with genotype
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Metabotropic glutamate receptor targets for neuropsychiatric disorders
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Mechanisms of perinatal brain damage and protective possibilities
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Oncology exploration: charting cancer medicinal chemistry space
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Status of text-mining techniques applied to biomedical text
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Role of glutamate receptors in the ventromedial hypothalamus in the regulation of female rat sexual behaviors: I. Behavioral effects of glutamate and its selective receptor agonists AMPA, NMDA and kainate
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Role of the central opioid system in the inhibition of water and salt intake induced by central administration of IL-1β in rats
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Functional investigations into the role of dopamine and serotonin in partial bilateral striatal 6-hydroxydopamine lesioned rats
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Psychosocial stress alters ethanol's effect on open field behaviors
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The application of mechanism-based PK/PD modeling in pharmacodynamic-based dose selection of muM17, a surrogate monoclonal antibody for efalizumab
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Effects of the mGluR8 agonist (S)-3,4-DCPG in the lateral amygdala on acquisition/expression of fear-potentiated startle, synaptic transmission, and plasticity
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Membrane voltage modulates the GABAA receptor gating in cultured rat hippocampal neurons
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Chronic pre-treatment with nicotine enhances nicotine-evoked striatal dopamine release and α6 and β3 nicotinic acetylcholine receptor subunit mRNA in the substantia nigra pars compacta of the rat
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Allosteric positive interaction of thymol with the GABAA receptor in primary cultures of mouse cortical neurons
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Opposing effects of AMPA and 5-HT1A receptor blockade on passive avoidance and object recognition performance: Correlation with AMPA receptor subunit expression in rat hippocampus
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Increased ethanol consumption and preference and decreased ethanol sensitivity in female FAAH knockout mice
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Chronic low-dose administration of nicotine facilitates recovery and synaptic change after focal ischemia in rats
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Intranasal Mucoadhesive Microemulsions of Clonazepam: Preliminary Studies on Brain Targeting
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Structure and Physical Stability of Hydrates and Thermotropic Mesophase of Calcium Benzoate
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Particle Size Limits to Meet USP Content Uniformity Criteria for Tablets and Capsules
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Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Cimetidine*
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Effect of design on the performance of a dry powder inhaler using computational fluid dynamics. Part 2: Air inlet size
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Locomotion is the major determinant of sibutramine-induced increase in energy expenditure
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Protein transduction by lipidic peptide dendrimers
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Effect of Food Intake on the Oral Absorption of Poorly Water-Soluble Drugs: In Vitro Assessment of Drug Dissolution and Permeation Assay System
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Multivariate data analysis as a fast tool in evaluation of solid state phenomena
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Development of a recursive finite difference pharmacokinetic model from an exponential model: Application to a propofol bolus*
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Chemical Kinetics and Aqueous Degradation Pathways of a New Class of Synthetic Ozonide Antimalarials
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Acrylic polymers as thickening agents for tetraglycol cosolvent
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Modulating β‐lapachone release from polymer millirods through cyclodextrin complexation
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Preparation of budesonide/γ‐cyclodextrin complexes in supercritical fluids with a novel SEDS method
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Level A in vitro-in vivo Correlation (IVIVC) Model with Bayesian Approach to Formulation Series
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Thermal Stability of Adenovirus type 2 as a Function of pH
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Towards an Understanding of the Molecular Mechanism of Solvation of Drug Molecules: A Thermodynamic Approach by Crystal Lattice Energy, Sublimation, and Solubility Exemplified by Hydroxybenzoic Acids
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Investigating acceptance in adjustment to chronic pain: Is acceptance broader than we thought?
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Maslinic acid as a feed additive to stimulate growth and hepatic protein-turnover rates in rainbow trout (Onchorhynchus mykiss)
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Influence of Ca, humic acid and pH on lead accumulation and toxicity in the fathead minnow during prolonged water-borne lead exposure
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Cu,Zn superoxide dismutase from Trematomus bernacchii: Functional conservation and erratic molecular evolution in Antarctic teleosts
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Inhibition of rainbow trout (Oncorhynchus mykiss) P450 aromatase activities in brain and ovarian microsomes by various environmental substances
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Rhodamine 123 permeability through the catfish intestinal wall: Relationship to thermal acclimation and acute temperature change
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Chronic pain couples: Perceived marital interactions and pain behaviours
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Spinal nerve lesion alters blood–spinal cord barrier function and activates astrocytes in the rat
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Sensory neuropathy and signs of central sensitization in patients with peripheral arterial disease
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Tonic inhibitory role of α4β2 subtype of nicotinic acetylcholine receptors on nociceptive transmission in the spinal cord in mice
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PAR-2 agonists activate trigeminal nociceptors and induce functional competence in the delta opioid receptor
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Stimulating the human midbrain to reveal the link between pain and blood pressure
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Effects of subcutaneous administration of glutamate on pain, sensitization and vasomotor responses in healthy men and women
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Interactive effects of naphthalene treatment and the onset of vitellogenesis on energy metabolism in liver and gonad, and plasma steroid hormones of rainbow trout Oncorhynchus mykiss
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Depletion of endogenous spinal 5-HT attenuates the behavioural hypersensitivity to mechanical and cooling stimuli induced by spinal nerve ligation
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Efficacy and safety of acupuncture for chronic uncomplicated neck pain: A randomised controlled study
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Tramadol, fentanyl and sufentanil but not morphine block voltage-operated sodium channels
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The psychometric quality and clinical usefulness of three pain assessment tools for elderly people with dementia
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Gabapentin and postoperative pain – a systematic review of randomized controlled trials
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Capsaicin-evoked brain activation and central sensitization in anaesthetised rats: A functional magnetic resonance imaging study
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Screening for pain phenotypes: Analysis of three congenic mouse strains on a battery of nine nociceptive assays
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Cognitive evaluation of disease-modifying efficacy of Galantamine and Memantine in the APP23 model
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Dehydroepiandrosterone (DHEA) attenuates cocaine-seeking behavior in the self-administration model in rats
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Key Word Index (Volume 16)
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The Montgomery Äsberg and the Hamilton ratings of depression: A comparison of measures
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Attenuation by Nardostachys jatamansi of 6-hydroxydopamine-induced parkinsonism in rats: behavioral, neurochemical, and immunohistochemical studies
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Rapid ethanol tolerance mediated by adaptations in acute tolerance in inbred mouse strains
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Differently lasting effects of prenatal and postnatal chronic clozapine/haloperidol on activity and memory in mouse offspring
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Chronic exercise decreases sensitivity to mu opioids in female rats: Correlation with exercise output
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Serotonin-1A receptor activity and expression modulate adolescent anabolic/androgenic steroid-induced aggression in hamsters
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Neuroactive steroids and affective disorders
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Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: Candidate mechanism for superior efficacy?
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Spontaneously hypertensive rats do not predict symptoms of attention-deficit hyperactivity disorder
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The potentiating effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on paraquat-induced neurochemical and behavioral changes in mice
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Effect of the flavonoid, oroxylin A, on transient cerebral hypoperfusion-induced memory impairment in mice
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Differential involvement of endogenous opioids in sucrose consumption and food reinforcement
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Typical and atypical antipsychotic drug effects on locomotor hyperactivity and deficits in sensorimotor gating in a genetic model of NMDA receptor hypofunction
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Morphine analgesic tolerance in 129P3/J and 129S6/SvEv mice
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Chronic fluoxetine upregulates arachidonic acid incorporation into the brain of unanesthetized rats
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Pharmacokinetics of repeated doses of intravenous cocaine across the menstrual cycle in rhesus monkeys
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Effects of prenatal exposure to alcohol on activity, anxiety, motor coordination, and memory in young adult Wistar rats
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Biochemical and functional aspects of crustacean hyperglycemic hormone in decapod crustaceans: Review and update
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Bothrops moojeni myotoxin-II, a Lys49-phospholipase A2 homologue: An example of function versatility of snake venom proteins
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Oxidative stress and protective effects of polyphenols: Comparative studies in human and rodent kidney. A review
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Serotonin modulation of caudal photoreceptor in crayfish
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Molecular impact of propiconazole on Daphnia magna using a reproduction-related cDNA array
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Acute actions of marine toxin latrunculin A on the electrophysiological properties of cultured dorsal root ganglion neurones
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In Appreciation
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Effect of calcineurin inhibitors on myotoxic activity of crotoxin and Bothrops asper phospholipase A2 myotoxins in vivo and in vitro
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Effects of acute and prolonged naphthalene exposure on brain monoaminergic neurotransmitters in rainbow trout (Oncorhynchus mykiss)
Fulltext Access 11 Pages 2006
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