March 27, 1827 and what happened later-the impact of psychiatry on evolutionary theory Fulltext Access 12 Pages 2006
Study of a novel indolin-2-ketone compound Z24 induced hepatotoxicity by NMR-spectroscopy-based metabonomics of rat urine, blood plasma, and liver extracts Fulltext Access 12 Pages 2006
Glutathione-S-transferase-omega [MMA(V) reductase] knockout mice: Enzyme and arsenic species concentrations in tissues after arsenate administration Fulltext Access 12 Pages 2006
Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated β-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6 Fulltext Access 12 Pages 2006
Agonist-independent alteration in β-adrenoceptor-G-protein-adenylate cyclase system in an equine model of recurrent airway obstruction Fulltext Access 12 Pages 2006
Serotonin 1A and 2A receptor densities, neurochemical and behavioural characteristics in two closely related mice strains after long-term isolation Fulltext Access 12 Pages 2006
Dysregulation of tau phosphorylation is a hypothesized point of convergence in the pathogenesis of alzheimer's disease, frontotemporal dementia and schizophrenia with therapeutic implications Fulltext Access 12 Pages 2006
Effects of selective neuronal nitric oxide synthase inhibition on sleep and wakefulness in the rat Fulltext Access 12 Pages 2006
Antidepressant drug induced alterations in binding to central dopamine transporter sites in the Wistar Kyoto rat strain Fulltext Access 12 Pages 2006
Are cholinergic enhancers beneficial for memory in schizophrenia? An event-related potentials (ERPs) study of rivastigmine add-on therapy in a crossover trial Fulltext Access 12 Pages 2006
Monoamine and motor responses to cocaine are co-deficient in the Fawn-Hooded depressed animal model Fulltext Access 12 Pages 2006
Darwinian models of depression: A review of evolutionary accounts of mood and mood disorders Fulltext Access 12 Pages 2006
Alteration of the spontaneous systemic autoimmune disease in (NZB × NZW)F1 mice by treatment with thimerosal (ethyl mercury) Fulltext Access 12 Pages 2006
Aerobic capacity, oxidant stress, and chronic obstructive pulmonary disease—A new take on an old hypothesis Fulltext Access 12 Pages 2006
Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis Fulltext Access 12 Pages 2006
From endothelium-derived hyperpolarizing factor (EDHF) to angiogenesis: Epoxyeicosatrienoic acids (EETs) and cell signaling Fulltext Access 12 Pages 2006
Mechanisms of the adaptive immune response inside the central nervous system during inflammatory and autoimmune diseases Fulltext Access 12 Pages 2006
Ginkgo biloba extract protects against ionizing radiation-induced oxidative organ damage in rats Fulltext Access 12 Pages 2006
Antipsychotic drugs disrupt normal development in Caenorhabditis elegans via additional mechanisms besides dopamine and serotonin receptors Fulltext Access 12 Pages 2006
Differential effects of ouabain on the vasodilator actions of nitric oxide and S-nitrosothiols in vivo: Relevance to the identity of EDRF/EDHF Fulltext Access 12 Pages 2006
Vascular calcium channels and high blood pressure: Pathophysiology and therapeutic implications Fulltext Access 12 Pages 2006
DNA damage, redox changes, and associated stress-inducible signaling events underlying the apoptosis and cytotoxicity in murine alveolar macrophage cell line MH-S by methanol-extracted Stachybotrys chartarum toxins Fulltext Access 12 Pages 2006
Prenatal 3,3′,4,4′,5-pentachlorobiphenyl exposure modulates induction of rat hepatic CYP 1A1, 1B1, and AhR by 7,12-dimethylbenz[a]anthracene Fulltext Access 12 Pages 2006
Mechanisms of action underlying the antiandrogenic effects of the fungicide prochloraz Fulltext Access 12 Pages 2006
Benzo(a)pyrene and 7,12-dimethylbenz(a)anthrecene differentially affect bone marrow cells of the lymphoid and myeloid lineages Fulltext Access 12 Pages 2006
TCDD decreases ATP levels and increases reactive oxygen production through changes in mitochondrial F0F1-ATP synthase and ubiquinone Fulltext Access 12 Pages 2006
Acrolein generation stimulates hypercontraction in isolated human blood vessels Fulltext Access 12 Pages 2006
Cardiovascular and blood coagulative effects of pulmonary zinc exposure Fulltext Access 12 Pages 2006
Availability and metabolism of 77Se-methylseleninic acid compared simultaneously with those of three related selenocompounds Fulltext Access 12 Pages 2006
Structure–activity relationships for the action of 11 pyrethroid insecticides on rat Nav1.8 sodium channels expressed in Xenopus oocytes Fulltext Access 12 Pages 2006
Chlorinated dibenzo-p-dioxins and dibenzofurans and the human immune system. 1. Blood cell receptors in volunteers with moderately increased body burdens Fulltext Access 12 Pages 2006
Monocrotaline pyrrole-induced megalocytosis of lung and breast epithelial cells: Disruption of plasma membrane and Golgi dynamics and an enhanced unfolded protein response Fulltext Access 12 Pages 2006
Role of the sodium-dependent phosphate co-transporters and of the phosphate complexes of uranyl in the cytotoxicity of uranium in LLC-PK1 cells Fulltext Access 12 Pages 2006
Changes in gene expression in human renal proximal tubule cells exposed to low concentrations of S-(1,2-dichlorovinyl)-l-cysteine, a metabolite of trichloroethylene Fulltext Access 12 Pages 2006
Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress Fulltext Access 12 Pages 2006
Calpastatin overexpression prevents progression of S-1,2-dichlorovinyl-l-cysteine (DCVC)-initiated acute renal injury and renal failure (ARF) in diabetes Fulltext Access 12 Pages 2006
Buprenorphine is protective against the depressive effects of norbuprenorphine on ventilation Fulltext Access 12 Pages 2006
A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine-mediated catalase upregulation Fulltext Access 12 Pages 2006
Interference by 2,3,7,8-tetrachlorodibenzo-p-dioxin with cultured mouse submandibular gland branching morphogenesis involves reduced epidermal growth factor receptor signaling Fulltext Access 12 Pages 2006
Up-regulation of interleukin-4 production via NF-AT/AP-1 activation in T cells by biochanin A, a phytoestrogen and its metabolites Fulltext Access 12 Pages 2006
Elevation of susceptibility to ozone-induced acute tracheobronchial injury in transgenic mice deficient in Clara cell secretory protein Fulltext Access 12 Pages 2006
An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers Fulltext Access 12 Pages 2006
Radiolytic and cellular reduction of a novel hypoxia-activated cobalt(III) prodrug of a chloromethylbenzindoline DNA minor groove alkylator Fulltext Access 12 Pages 2006
Activation of murine peritoneal macrophages by sulfated exopolysaccharide from marine microalga Gyrodinium impudicum (strain KG03): Involvement of the NF-κB and JNK pathway Fulltext Access 12 Pages 2006
Tumor-induced thymic involution via inhibition of IL-7Rα and its JAK-STAT signaling pathway: Protection by black tea Fulltext Access 12 Pages 2006
Dexamethasone, colchicine and iodine-lithium-α-dextrin act differentially on the oxidative burst and endotoxin tolerance induction in vitro in patients with Behçet's disease Fulltext Access 12 Pages 2006
Evaluation of immunotoxic and immunodisruptive effects of inorganic arsenite on human monocytes/macrophages Fulltext Access 12 Pages 2006
Estrogen stimulates transcription of human immunodeficiency virus type 1 (HIV-1) Fulltext Access 12 Pages 2006
Novel p38 mitogen-activated protein kinase inhibitor R-130823 protects cartilage by down-regulating matrix metalloproteinase-1,-13 and prostaglandin E2 production in human chondrocytes Fulltext Access 12 Pages 2006
4-O-Methylgallic acid suppresses inflammation-associated gene expression by inhibition of redox-based NF-κB activation Fulltext Access 12 Pages 2006
Inflammatory biomarker, neopterin, enlarges splenic mast-cell-progenitor pool: Prominent impairment of responses in age-related stromal cell-impairment mouse SCI/SAM Fulltext Access 12 Pages 2006
Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt Fulltext Access 12 Pages 2006
Activation of phosphoinositide 3-kinase and Src family kinase is required for respiratory burst in rat neutrophils stimulated with artocarpol A Fulltext Access 12 Pages 2006
Modulation of antigen-specific T cell response by a non-mitogenic anti-CD3 antibody Fulltext Access 12 Pages 2006
Structure–activity relationship for nucleoside analogs as inhibitors or substrates of adenosine kinase from Mycobacterium tuberculosis: I. Modifications to the adenine moiety Fulltext Access 12 Pages 2006
Epigenetic control of CTCFL/BORIS and OCT4 expression in urogenital malignancies Fulltext Access 12 Pages 2006
Different fates of intracellular glutathione determine different modalities of apoptotic nuclear vesiculation Fulltext Access 12 Pages 2006
Interaction between the insulin receptor and Grb14: A dynamic study in living cells using BRET Fulltext Access 12 Pages 2006
Modulation of mitochondrial metabolic function by phorbol 12-myristate 13-acetate through increased mitochondrial translocation of protein kinase Cα in C2C12 myocytes Fulltext Access 12 Pages 2006
The synthetic cannabinoid WIN 55,212-2 increases COX-2 expression and PGE2 release in murine brain-derived endothelial cells following Theiler's virus infection Fulltext Access 12 Pages 2006
Kinetics of nonpeptide antagonist binding to the human gonadotropin-releasing hormone receptor: Implications for structure–activity relationships and insurmountable antagonism Fulltext Access 12 Pages 2006
Induction of G2/M phase arrest and apoptosis of human leukemia cells by potent antitumor triazoloacridinone C-1305 Fulltext Access 12 Pages 2006
2′,4′,6′-Tris(methoxymethoxy) chalcone attenuates hepatic stellate cell proliferation by a heme oxygenase-dependent pathway Fulltext Access 12 Pages 2006
Metal influence on metallothionein synthesis in the hydrothermal vent mussel Bathymodiolus thermophilus Fulltext Access 12 Pages 2006
Antioxidative stress proteins and their gene expression in brown trout (Salmo trutta) from three rivers with different heavy metal levels Fulltext Access 12 Pages 2006
Electrocardiogram, hemodynamics, and core body temperatures of the normal freely moving cynomolgus monkey by remote radiotelemetry Fulltext Access 12 Pages 2006
Adenosine receptor-mediated coronary vascular protection in post-ischemic mouse heart Fulltext Access 12 Pages 2006
Double-stranded RNA-dependent protein kinase (PKR) is a stress-responsive kinase that induces NFκB-mediated resistance against mercury cytotoxicity Fulltext Access 12 Pages 2006
Oxidative stress protection by newly synthesized nitrogen compounds with pharmacological potential Fulltext Access 12 Pages 2006
Comparison of opioid receptor distributions in the rat central nervous system Fulltext Access 12 Pages 2006
The effects of acute corticosterone on lithium chloride-induced conditioned place aversion and locomotor activity in rats Fulltext Access 12 Pages 2006
Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice Fulltext Access 12 Pages 2006
Spatio-temporal properties of 5-lipoxygenase expression and activation in the brain after focal cerebral ischemia in rats Fulltext Access 12 Pages 2006
Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1 Fulltext Access 12 Pages 2006
Use of arterially perfused rabbit ventricular wedge in predicting arrhythmogenic potentials of drugs Fulltext Access 12 Pages 2006
Use of canalicular membrane vesicles (CMVs) from rats, dogs, monkeys and humans to assess drug transport across the canalicular membrane Fulltext Access 12 Pages 2006
Development and characterization of LLC-PK1 cells containing Sprague–Dawley rat Abcb1a (Mdr1a): Comparison of rat P-glycoprotein transport to human and mouse Fulltext Access 12 Pages 2006
Structural and functional characterization of microcystin detoxification-related liver genes in a phytoplanktivorous fish, Nile tilapia (Oreochromis niloticus) Fulltext Access 12 Pages 2006
Electrocardiogram, hemodynamics, and core body temperatures of the normal freely moving laboratory beagle dog by remote radiotelemetry Fulltext Access 12 Pages 2006
Mexican migrant ethnopharmacology: Pharmacopoeia, classification of medicines and explanations of efficacy Fulltext Access 12 Pages 2006
The immunostimulant RU41740 from Klebsiella pneumoniae activates human cells in whole blood to potentially stimulate innate and adaptive immune responses Fulltext Access 12 Pages 2006
CpG oligodeoxynucleotide-induced immunity prevents growth of germinal center-derived B lymphoma cells Fulltext Access 12 Pages 2006
Structure and biological activity of protopanaxatriol-type saponins from the roots of Panax notoginseng Fulltext Access 12 Pages 2006
Decreased intracellular TLR9 confers hyporesponsiveness of RAW264.7 cells to subsequent CpG ODN challenge Fulltext Access 12 Pages 2006