The role of ERK signaling and the P2X receptor on mechanical pain evoked by movement of inflamed knee joint Fulltext Access 11 Pages 2006
Activation of protein kinase B/Akt signaling pathway contributes to mechanical hypersensitivity induced by capsaicin Fulltext Access 11 Pages 2006
Neuroprotection by tetramethylpyrazine against ischemic brain injury in rats Fulltext Access 11 Pages 2006
Contribution of brainstem GABAA synaptic transmission to morphine analgesic tolerance Fulltext Access 11 Pages 2006
Lumbar instrumented fusion compared with cognitive intervention and exercises in patients with chronic back pain after previous surgery for disc herniation: A prospective randomized controlled study Fulltext Access 11 Pages 2006
The effects of Botulinum Toxin type A on capsaicin-evoked pain, flare, and secondary hyperalgesia in an experimental human model of trigeminal sensitization Fulltext Access 11 Pages 2006
Contact heat-evoked temporal summation: Tonic versus repetitive-phasic stimulation Fulltext Access 11 Pages 2006
Long-term effectiveness of a patient and family pain education program on overcoming barriers to management of cancer pain Fulltext Access 11 Pages 2006
Morphological alterations and induction of oxidative stress in glial cells caused by the branched-chain α-keto acids accumulating in maple syrup urine disease Fulltext Access 11 Pages 2006
Post-operative pain behavior in rats is reduced after single high-concentration capsaicin application Fulltext Access 11 Pages 2006
Distinct forebrain activity patterns during deep versus superficial pain Fulltext Access 11 Pages 2006
Mass spectrometrical identification of brain proteins including highly insoluble and transmembrane proteins Fulltext Access 11 Pages 2006
Potentiation of morphine antinociception by pentobarbital in female vs. male rats Fulltext Access 11 Pages 2006
Pharmacological assessment of the freezing, antinociception, and exploratory behavior organized in the ventrolateral periaqueductal gray Fulltext Access 11 Pages 2006
Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCε-mediated phosphorylation at S800 Fulltext Access 11 Pages 2006
Orofacial cold hyperalgesia due to infraorbital nerve constriction injury in rats: Reversal by endothelin receptor antagonists but not non-steroidal anti-inflammatory drugs Fulltext Access 11 Pages 2006
Purinergic receptors modulate MAP kinases and transcription factors that control microglial inflammatory gene expression Fulltext Access 11 Pages 2006
Clusterin in cerebrospinal fluid: Analysis of carbohydrates and quantification of native and glycosylated forms Fulltext Access 11 Pages 2006
Les anévrysmes intracrâniens et leur traitement endovasculaire par l'utilisation de coils Fulltext Access 11 Pages 2006
Anti-Parkinsonian agents have anti-amyloidogenic activity for Alzheimer's β-amyloid fibrils in vitro Fulltext Access 11 Pages 2006
The neural cell adhesion molecule NCAM regulates neuritogenesis by multiple mechanisms of interaction Fulltext Access 11 Pages 2006
Estimation of the hypothermic component in neuroprotection provided by cannabinoids following cerebral ischemia Fulltext Access 11 Pages 2006
Solid state interactions between the proton pump inhibitor omeprazole and various enteric coating polymers Fulltext Access 12 Pages 2006
Comparison between dehydration and desolvation kinetics of fluconazole monohydrate and fluconazole ethylacetate solvate using three different methods Fulltext Access 12 Pages 2006
Determination of solubility profiles of eflucimibe polymorphs: Experimental and modeling Fulltext Access 12 Pages 2006
Identification, Preparation, and Characterization of Several Polymorphs and Solvates of Terazosin Hydrochloride Fulltext Access 12 Pages 2006
The Influence of Actuation Parameters on in Vitro Testing of Nasal Spray Products Fulltext Access 12 Pages 2006
The novel antidyskinetic drug sarizotan elicits different functional responses at human D2-like dopamine receptors Fulltext Access 12 Pages 2006
Thermodynamic modeling of activity coefficient and prediction of solubility: Part 2. Semipredictive or semiempirical models Fulltext Access 12 Pages 2006
Catanionic mixtures involving a drug: A rather general concept that can be utilized for prolonged drug release from gels Fulltext Access 12 Pages 2006
Disassembly and reassembly of yeastâderived recombinant human papillomavirus virusâlike particles (HPV VLPs) Fulltext Access 12 Pages 2006
Towards an understanding of the molecular mechanism of solvation of drug molecules: A thermodynamic approach by crystal lattice energy, sublimation, and solubility exemplified by paracetamol, acetanilide, and phenacetin Fulltext Access 12 Pages 2006
Multiscale Modelling Methodology for Virtual Prototyping of Effervescent Tablets Fulltext Access 12 Pages 2006
Stability profiles of drug products extended beyond labeled expiration dates Fulltext Access 12 Pages 2006
Towards an Understanding of the Structurally Based Potential for Mechanically Activated Disordering of Small Molecule Organic Crystals Fulltext Access 12 Pages 2006
Novel Colon-Specific Microspheres With Highly Dispersed Hydroxycamptothecin Cores: Their Preparation, ReleaseBehavior, and Therapeutic Efficiency Against Colonic Cancer Fulltext Access 12 Pages 2006
Aluminum hydroxide adjuvant produced under constant reactant concentration Fulltext Access 12 Pages 2006
Induction of UGT1A6 isoform by inflammatory conditions in rat astrocytes Fulltext Access 12 Pages 2006
Schizophrenia-associated neural growth factors in peripheral blood. A review Fulltext Access 12 Pages 2006
Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA (“Ecstasy”) and MDA (“Love”) Fulltext Access 12 Pages 2006
Immediate-early gene expression in the central nucleus of the amygdala is not specific for anxiolytic or anxiogenic drugs Fulltext Access 12 Pages 2006
In vitro and in vivo characterization of F-97013-GD, a partial 5-HT1A agonist with antipsychotic- and antiparkinsonian-like properties Fulltext Access 12 Pages 2006
Irt > t schedule controlled behavior in ‘learned-helpless’ rats: Effects from a cannabinoid agonist Fulltext Access 12 Pages 2006
Chronic DHEAS administration facilitates hippocampal long-term potentiation via an amplification of Src-dependent NMDA receptor signaling Fulltext Access 12 Pages 2006
SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4′-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role Fulltext Access 12 Pages 2006
Alterations in 5-HT2A receptor signaling in male and female transgenic rats over-expressing either Gq or RGS-insensitive Gq protein Fulltext Access 12 Pages 2006
Glutamate receptors in the raphe pallidus mediate brown adipose tissue thermogenesis evoked by activation of dorsomedial hypothalamic neurons Fulltext Access 12 Pages 2006
Neuroanatomical and pharmacological assessment of Fos expression induced in the rat brain by the phosphodiesterase-4 inhibitor 6-(4-pyridylmethyl)-8-(3-nitrophenyl) quinoline Fulltext Access 12 Pages 2006
Evaluation of Ingredient Concentration in Powders Using Two-Speed Photon Migration Theory and Measurements Fulltext Access 12 Pages 2006
The neurotoxin 2′-NH2-MPTP degenerates serotonin axons and evokes increases in hippocampal BDNF Fulltext Access 12 Pages 2006
Molecular analysis of the interaction of the pyrazine derivatives RPR119990 and RPR117824 with human AMPA-type glutamate receptor channels Fulltext Access 12 Pages 2006
Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain Fulltext Access 12 Pages 2006
Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes Fulltext Access 12 Pages 2006
Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: Evidence for altered striatal function Fulltext Access 12 Pages 2006
Cross talk between nitric oxide and ERK1/2 signaling pathway in the spinal cord mediates naloxone-precipitated withdrawal in morphine-dependent rats Fulltext Access 12 Pages 2006
Retigabine and flupirtine exert neuroprotective actions in organotypic hippocampal cultures Fulltext Access 12 Pages 2006
QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine Fulltext Access 12 Pages 2006
Tolerance to morphine analgesia: Evidence for stimulus intensity as a key factor and complete reversal by a glycine site-specific NMDA antagonist Fulltext Access 12 Pages 2006
Bias from industry trial funding? A framework, a suggested approach, and a negative result Fulltext Access 12 Pages 2006
Daily patterns of ethanol drinking in peri-adolescent and adult alcohol-preferring (P) rats Fulltext Access 12 Pages 2006
Behavioural and hypothalamic molecular effects of the anti-cancer agent cisplatin in the rat: A model of chemotherapy-related malaise? Fulltext Access 12 Pages 2006
GW274150, a novel and highly selective inhibitor of the inducible isoform of nitric oxide synthase (iNOS), shows analgesic effects in rat models of inflammatory and neuropathic pain Fulltext Access 12 Pages 2006
Influence of low doses of naltrexone on morphine antinociception and morphine tolerance in male and female rats of four strains Fulltext Access 12 Pages 2006
Cerebral activation during thermal stimulation of patients who have burning mouth disorder: An fMRI study Fulltext Access 12 Pages 2006
Loss of expectation-related mechanisms in Alzheimer’s disease makes analgesic therapies less effective Fulltext Access 12 Pages 2006
Increased sodium channel immunofluorescence at myelinated and demyelinated sites following an inflammatory and partial axotomy lesion of the rat infraorbital nerve Fulltext Access 12 Pages 2006
Differential effects of endogenous cysteine analogs on peripheral thermal nociception in intact rats Fulltext Access 12 Pages 2006
Multiple vaccine and pyridostigmine interactions: Effects on cognition, muscle function and health outcomes in marmosets Fulltext Access 12 Pages 2006
The fear-avoidance model of chronic pain: Validation and age analysis using structural equation modeling Fulltext Access 12 Pages 2006
Signaling pathway of morphine induced acute thermal hyperalgesia in mice Fulltext Access 12 Pages 2006
Coping with rheumatoid arthritis pain in daily life: Within-person analyses reveal hidden vulnerability for the formerly depressed Fulltext Access 12 Pages 2006
Cortical effects of anticipation and endogenous modulation of visceral pain assessed by functional brain MRI in irritable bowel syndrome patients and healthy controls Fulltext Access 12 Pages 2006
Dopamine D2 receptor gene variants and quantitative measures of positive and negative symptom response following clozapine treatment Fulltext Access 12 Pages 2006
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders Fulltext Access 12 Pages 2006
Effects of melatonin and agomelatine in anxiety-related procedures in rats: Interaction with diazepam Fulltext Access 12 Pages 2006
Increase in apoptosis with neural differentiation and shortening of the lifespan of P19 cells overexpressing tau Fulltext Access 12 Pages 2006
Enhanced bioavailability of a new thiazolidine derivative FPFS-410, an antidiabetic and lipid-lowering drug, after oral administration of its hydroxypropyl-β-cyclodextrin complex to bile duct-cannulated rats Fulltext Access 12 Pages 2006
Sertaconazole/hydroxypropyl-β-cyclodextrin complexation: Isothermal titration calorimetry and solubility approaches Fulltext Access 12 Pages 2006
Grid-Based Molecular Modeling for Pharmaceutical Salt Screening: Case Example of 3,4,6,7,8,9-Hexahydro-2H-pyrimido (1,2-a) Pyrimidinium Acetate Fulltext Access 12 Pages 2006
Intraluminal drug and formulation behavior and integration in in vitro permeability estimation: A case study with amprenavir Fulltext Access 12 Pages 2006
Carrier-mediated hepatic uptake of a novel nonrenal excretion type uric acid generation inhibitor, Y-700 Fulltext Access 12 Pages 2006
Alteration of the intravenous pharmacokinetics of a synthetic ozonide antimalarial in the presence of a modified cyclodextrin Fulltext Access 12 Pages 2006
Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants Fulltext Access 12 Pages 2006
Amygdala kindling differentially regulates the expression of the elements involved in TRH transmission Fulltext Access 12 Pages 2006
Structure–activity relationship analysis of antioxidant ability and neuroprotective effect of gallic acid derivatives Fulltext Access 12 Pages 2006
Prediction of human drug clearance from animal data: Application of the rule of exponents and 'fu corrected intercept method' (FCIM) Fulltext Access 12 Pages 2006
The effects of doxycycline administration on amino acid neurotransmitters in an animal model of neonatal hypoxia-ischemia Fulltext Access 12 Pages 2006
Dopamine transporter-mediated cytotoxicity of 6-hydroxydopamine in vitro depends on expression of mutant α-synucleins related to Parkinson's disease Fulltext Access 12 Pages 2006
Functional characterization of sodium channel blockers by membrane potential measurements in cerebellar neurons: Prediction of compound preference for the open/inactivated state Fulltext Access 12 Pages 2006
TDIQ (5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline) exhibits anxiolytic-like activity in a marble-burying assay in mice Fulltext Access 12 Pages 2006
Both corticotropin-releasing factor and apomorphine reduce prepulse inhibition following repeated central infusion of corticotropin-releasing factor Fulltext Access 12 Pages 2006
Neurosteroids, neuroactive steroids, and symptoms of affective disorders Fulltext Access 12 Pages 2006
Multiple vaccine and pyridostigmine interactions: Effects on EEG and sleep in the common marmoset Fulltext Access 12 Pages 2006