Study on the oxidation of fibrinogen using Fe3O4 magnetic nanoparticles and its influence to the formation of fibrin

An efficient oxidative stress using Fe3O4 magnetic nanoparticles as peroxidase mimetics was developed to study the structure and polymerization of fibrinogen molecules. Oxidative stress could influence the equilateral junctions of protofibrils and the cross-linking patterns, decrease the fibre size, form a higher proportion of branching and a denser aggregation state.70