کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10156061 1666370 2019 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
In vitro Cytotoxicity, MMP and ROS activity of green synthesized nickel oxide nanoparticles using extract of Terminalia chebula against MCF-7 cells
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد فناوری نانو (نانو تکنولوژی)
پیش نمایش صفحه اول مقاله
In vitro Cytotoxicity, MMP and ROS activity of green synthesized nickel oxide nanoparticles using extract of Terminalia chebula against MCF-7 cells
چکیده انگلیسی
Nanotechnology has been offered the prospect for the development of novel nanomaterials with countless potential applications in natural sciences and clinical pharmaceutical. This study described the analysis of green synthesized nickel oxide nanoparticles (NPs) using the extract of Terminalia chebula. The Green synthesized NiO NPs were characterized by Transmission Electron Microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), energy dispersive X-rays Analysis (EDAX) and ultraviolet-visible spectroscopy (UV-Vis). Green synthesized NiO NPs displayed the toxicity to breast cancerous cells in a dose-dependent way from 0 to 100 µg/mL showing noticeable cell viability, Reactive oxygen species (ROS) activity and liberating of mitochondrial membrane potential (MMP). The statistical scrutiny was also done on the experimental outcomes to check the value and precision of the effects, with p-values <0.05 selected as significant. The planned approach deliberates the NiO NPs as a function of phenolic extracts of T. chebula with vast potential for several biological and biomedical applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Letters - Volume 234, 1 January 2019, Pages 129-133
نویسندگان
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