Stimulatory effects of the ionic products from Ca-Mg-Si bioceramics on both osteogenesis and angiogenesis in vitro

Ideal biomaterials for bone tissue engineering should have capability to guide osteogenic differentiation of mesenchymal stem cells and, at the same time, to stimulate angiogenesis of endothelia cells. In this study, it was found that three Ca, Mg and Si-containing bioceramics can potentially induce osteogenesis and angiogenesis.