کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10267015 | 459433 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Study on electrochemical behavior of a diphtheria immunosensor based on silica/silver/gold nanoparticles and polyvinyl butyral as matrices
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
In this paper, electrochemical behavior of a diphtheria immunosensor modified with nano-size conductor and semiconductor, as a mode of silica/gold/silver nanoparticles, has been investigated. Potentiometric immunosensor, cyclic voltammetry, and electrochemical impedance techniques were used to investigate the immobilization of diphtheria antibody on silica/gold/silver colloids. In the impedance spectroscopic study, an obvious difference of the electron transfer resistance between the silica-colloid modified electrode and the gold/silver-colloid modified electrodes was observed. The cyclic voltammogram tends to be more irreversible on silica colloids. Subsequently, using the silica colloid-modified immunosensor by potentiometry as a mode, it is found that the resulting immunosensor exhibited fast potentiometric response (<3 min), high sensitivity and good reproducibility. Moreover, analytical results of several specimens obtained using the silica colloid-modified immunosensor are in satisfactory agreement with those given by the ELISA method, implying a promising alternative approach for detecting diphtheria antigen in the clinical diagnosis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochemistry Communications - Volume 7, Issue 2, February 2005, Pages 177-182
Journal: Electrochemistry Communications - Volume 7, Issue 2, February 2005, Pages 177-182
نویسندگان
Dianping Tang, Ruo Yuan, Yaqin Chai, Yingzi Fu,