Selective surface reactions for Janus ORMOSIL particles with multiple functional groups using an ordered monolayer film at liquid-liquid interface

► Monodispersed Janus ORMOSIL particles with multiple functional groups were prepared. ► A monolayer film was obtained by self-assembly of ORMOSIL particles at interface. ► Photopolymerization of a monolayer yield a rigid film to perform further reaction. ► Selective surface reaction of a rigid film produced Janus ORMOSIL particles.