Speech comprehension aided by multiple modalities: Behavioural and neural interactions

► We varied properties of audiovisual sentences in behavioural and fMRI experiments. ► Visual cues to intelligibility were more effective when auditory clarity was low. ► Linguistic manipulations affected intelligibility most at the highest level of auditory clarity. ► Fronto-parietal regions identified as sites of multi-cue interaction. ► Activation in left IFG and STS predicted individual differences in comprehension.