Administration of prebiotic inulin suppresses 1,2 dimethylhydrazine dihydrochloride induced procarcinogenic biomarkers fecal enzymes and preneoplastic lesions in early colon carcinogenesis in Sprague Dawley rats

► ACF counts were less with inulin and lactulose as compared with the DMH animals. ► Activity of β-glucuronidase and β-glucosidase decreased in inulin + DMH treated animals. ► Inulin was better as compared with lactulose in reducing early colon carcinogenesis.