کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10553970 | 967946 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Combined liquid and solid-surface room temperature fluorimetric determination of naproxen and salicylate in serum
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A rapid and sensitive method for the determination of naproxen and salicylate in serum is presented. The employed strategy combines solid-phase extraction on a reverse-phase membrane with spectrofluorimetry. Solid-phase extraction under optimum pH conditions makes NX to be retained over the solid surface (where it is directly determined by a fluorimetric technique). Salicylate passes through the disk and is also fluorimetrically determined, but in solution. The linear calibration ranges for NX in the membrane and salicylate in solution were 0.014-0.250 and 0.010-0.250 μg mlâ1, respectively. The lowest value, in each case, is the corresponding limit of quantitation. The performance of the method is demonstrated with the successful determination of both drugs in spiked and real human serum samples.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 37, Issue 1, 7 February 2005, Pages 149-155
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 37, Issue 1, 7 February 2005, Pages 149-155
نویسندگان
G.A. Ibañez, G.M. Escandar,