Trimethyl and carboxymethyl chitosan carriers for bio-active polymer-inorganic nanocomposites

► Synthesis and characterization of new POM-TMC nanocomposites. ► Biopolymer-dependent properties of POM-TMC vs. POM-CMC nanoparticles. ► Investigation of POM-TMC cellular uptake pathways. ► Anticancer properties of POM-TMC composite with productive TMC matrix effect.