Cationic polypeptide micelle-based antigen delivery system: A simple and robust adjuvant to improve vaccine efficacy

Polypeptide micelle-based vaccine delivery system could not only promote antibody responses, but also co-encapsulate antigens (e.g. OVA) and immunopotentiators (e.g. PIC), thereby synergistically augmenting CD8 T cell-mediated tumor cell lysis.123