Anorexic behavior and elevation of hypothalamic malonyl-CoA in socially defeated rats

► Socially defeated rats showed suppressed body weight gain. ► Socially defeated rats showed decreased food intake during the dark phase. ► Elevation of hypothalamic malonyl-CoA was observed in socially defeated rats. ► Anorexia under social stress may be involved in hypothalamic malonyl-CoA.