High circulating levels of S100A8/A9 complex (calprotectin) in male Japanese with abdominal adiposity and dysregulated expression of S100A8 and S100A9 in adipose tissues of obese mice

► High serum levels of S100A8/A9 complex in obesity. ► Circulating S100A8/A9 complex levels correlated significantly with abdominal adiposity. ► High S100A8 mRNA levels in mature adipocyte fraction of obese mice. ► High S100A9 mRNA levels in stromal vascular cell fraction of obese mice.