Degradome sequencing reveals an endogenous microRNA target in C. elegans

► Degradome sequencing was employed to directly detect endogenous miRNA cleavage targets in C. elegans. ► miR-249 directs the cleavage of the ZK637.6 pseudogene transcript. ► The expression of the ZK637.6 pseudogene transcript is negatively correlated with the expression of miR-249.