miR-518b is down-regulated, and involved in cell proliferation and invasion by targeting Rap1b in esophageal squamous cell carcinoma

► miR-518b is down-regulated in ESCC tissues. ► miR-518b inhibits cell proliferation and invasion of ESCC cells in vitro. ► miR-518b directly targets and down-regulates Rap1b in ESCC cells.