Cadherin complexity: recent insights into cadherin superfamily function in C. elegans

► HMR-1/cadherin cooperates with SAX-7/L1CAM and the Rac pathway to drive gastrulation. ► PAR-3/Bazooka and PAR-6 function differently between germ layers to localize HMR-1. ► SRGP-1/Slit-RoboGAP interacts with the CCC to promote epidermal morphogenesis. ► HMP-1/α-catenin experiments reveal domains important for α-catenin function. ► FMI-1/Flamingo promotes neural morphogenesis in conjunction with CDH-4/Fat-like.