کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10940338 | 1095478 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Stromal cell-derived factor-1 (SDF-1) expression in embryonic mouse cerebral cortex starts in the intermediate zone close to the pallial-subpallial boundary and extends progressively towards the cortical hem
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کلمات کلیدی
SDF-1PSA-NCAMCXCR4CXCL12Interneuron - اینترنورون، نورون رابط، نورون بینابینیPallium - بیزار شدنEmbryo - جنینDevelopment - رشدsubpallium - زیرمجموعهCytokine - سیتوکینcortical plate - صفحه قشرbasal ganglia - عقدههای قاعدهایcerebral cortex - قشر مغزintermediate zone - منطقه متوسطMigration - مهاجرتneocortex - نوقشر، نئوکورتکسHippocampus - هیپوکامپ Chemokine - کموکاین یا کموکین Cortical hem - گوشه گوشه
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیولوژی سلول
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Stromal cell-derived factor-1 (SDF-1) expression in embryonic mouse cerebral cortex starts in the intermediate zone close to the pallial-subpallial boundary and extends progressively towards the cortical hem Stromal cell-derived factor-1 (SDF-1) expression in embryonic mouse cerebral cortex starts in the intermediate zone close to the pallial-subpallial boundary and extends progressively towards the cortical hem](/preview/png/10940338.png)
چکیده انگلیسی
We describe the onset and the expansion of stromal cell-derived factor 1 (SDF-1) expression in the intermediate zone of embryonic mouse cerebral cortex between embryonic days (E)11.5 and 18.5, and on postnatal day 1. Using in situ hybridisation with a digoxigenin-labeled probe, SDF-1 mRNA was detectable by E 12.5 in a small area of the intermediate zone just dorsal to the pallial-subpallial boundary. During the following days, SDF-1 expression extended towards the dorso-lateral pallium, and then the hippocampus and cortical hem. The position of the SDF-1 positive cells within the intermediate zone was closely correlated with the stream of tangentially migrating cells carrying the polysialylated form of neural cell adhesion molecule (PSA-NCAM). However, whereas these cells form a ventro-dorsal stream passing from the subpallium into the pallium, SDF-1 was not detectable on the ventral side of the pallial-subpallial boundary at any of the developmental stages studied. By E 16.5, the intensity of SDF-1 hybridisation signal in the intermediate zone decreased, to become undetectable by E 18.5.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene Expression Patterns - Volume 5, Issue 3, February 2005, Pages 317-322
Journal: Gene Expression Patterns - Volume 5, Issue 3, February 2005, Pages 317-322
نویسندگان
Dorothée Daniel, Mireille Rossel, Tatsunori Seki, Norbert König,