کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
11026354 | 1666395 | 2019 | 18 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
In-gel study of the effect of magnetic nanoparticles immobilization on their heating efficiency for application in Magnetic Fluid Hyperthermia
ترجمه فارسی عنوان
مطالعه درون ژل اثر مهار نانو ذرات مغناطیسی بر راندمان حرارت آنها برای کاربرد در هیپرترمی مایع مغناطیسی
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
فیزیک ماده چگال
چکیده انگلیسی
Recent studies on magnetic nanoparticles (MNPs) used for Magnetic Fluid Hyperthermia treatments have shown that Brownian rotation is suppressed when they are confined within a cell. To investigate this effect we conducted a systematic study of the Specific Absorption Rate (SAR) of colloidal suspensions of MNPs in water and gels at different agarose concentration. SAR measurements were conducted by varying the frequency (fâ¯=â¯110-990â¯kHz) and amplitude (up to 17â¯kA/m) of the applied alternating magnetic field (AMF). MNP samples with different diameter (dâ¯=â¯10, 14, and 18â¯nm) were used. Our results show that Néel relaxation dominates SAR with negligible contribution from Brownian motion for smaller MNPs (dâ¯=â¯10â¯nm). For the largest MNPs (dâ¯=â¯18â¯nm) we observed a more significant SAR decrease in gel suspensions as compared to those in solution. In particular, when applying AMFs as the ones used in a clinical setting (16.2â¯kA/m at fâ¯=â¯110â¯kHz), we measured SAR value of 67â¯W/g in solution and 25â¯W/g in gel. This experimental finding demonstrates that investigation of MNPs properties should be conducted in media with viscosity similar to the one found in mammalian tissues.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Magnetism and Magnetic Materials - Volume 471, 1 February 2019, Pages 504-512
Journal: Journal of Magnetism and Magnetic Materials - Volume 471, 1 February 2019, Pages 504-512
نویسندگان
Matteo Avolio, Andrea Guerrini, Francesca Brero, Claudia Innocenti, Claudio Sangregorio, Marco Cobianchi, Manuel Mariani, Francesco Orsini, Paolo Arosio, Alessandro Lascialfari,