کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1196302 964555 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Investigating the Effect of Mixing Ratio on Molar Mass Distributions of Synthetic Polymers determined by MALDI-TOF Mass Spectrometry using Design of Experiments
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Investigating the Effect of Mixing Ratio on Molar Mass Distributions of Synthetic Polymers determined by MALDI-TOF Mass Spectrometry using Design of Experiments
چکیده انگلیسی

It is well known that the mixing ratio affects the molar mass distribution of synthetic polymers determined by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Surely, the molar mixing ratio determines whether a mass spectrum will be obtained or not. However, depending on the mass range, several effects such as multimer formation occur, which might be a source of errors in molar mass distribution calculations. In this study, the effect of mixing ratio was investigated for several synthetic polymers, including polystyrene (PS), poly(dimethylsiloxane) (PDMS), poly(ethylene glycol) (PEG), and poly(methyl methacrylate) (PMMA) using statistical designs of experiments. The 23 full factorial design was found to be suitable in the study of more than 1000 samples. The obtained MALDI mass spectra as well as the ANOVA statistics show that the mixing ratio affects the molar mass distribution. The optimal mixing ratio for a defined synthetic polymer depends on the studied combination (matrix, cationization reagent, solvent).

Graphical AbstractApplying chemometrics the effect of mixing ratio on molar mass distributions of synthetic polymers was investigated.Figure optionsDownload high-quality image (159 K)Download as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Society for Mass Spectrometry - Volume 21, Issue 11, November 2010, Pages 1870–1875
نویسندگان
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