کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1219661 | 1494542 | 2016 | 9 صفحه PDF | دانلود رایگان |
• In vitro digestion coupled to epithelium absorptive models for anthocyanins.
• Gastric and intestinal anthocyanin transport efficiency by MKN-28 and Caco-2 cells.
• Gastric mucosa is the preferred site of anthocyanin absorption.
The bioaccessibility of the anthocyanins from peel powder of jabuticaba, jamelão and jambo fruits under gastro-intestinal conditions and their gastric and intestinal absorption was examined in order to estimate anthocyanin transport efficiency (ATE). Thus, in vitro digestion coupled to epithelium absorptive models (gastric MKN-28 and intestinal Caco-2) was applied independently for each phase. The bioaccessibility of anthocyanins after gastric digestion were 13% for jabuticaba, 45% for jambo and 65% for jamelão, whereas intestinal bioaccessibility were 10% for jabuticaba, 15% for jambo and 45% for jamelão. The assays showed that, applying the MKN-28 cell model, the ATE were 19.7, 9.7 and 14.1%, respectively, for jambo, jabuticaba, and jamelão powders, whereas using the Caco-2 cell model these results were 0.8, 0.2 and 0.3%, respectively. In conclusion gastric mucosa plays an important role in anthocyanin's absorption.
Journal: Journal of Functional Foods - Volume 24, June 2016, Pages 373–381