Enhanced chemiluminescence CdSe quantum dots by histidine and tryptophan

• For first time, we present a simple imidazole–H2O2–CdSe QDs CL system for recognition histidine or tryptophan.
• The intensity of the chemiluminescence reaction of CdSe quantum dots enhances with addition histidine or tryptophan.
• The chemiluminescence reaction of CdSe quantum dots shows high selectivity and sensitivity to histidine or tryptophan.

The enhancing effect of histidine and tryptophan on chemiluminescence (CL) of CdSe quantum dots (QDs)–H2O2 system was studied. This reaction is based on the catalytic effect of amino acids, causing a significant increase in the light emission, as a result of the reaction of quantum dots (QDs) with hydrogen peroxide. In the optimum conditions, this method was satisfactorily described by linear calibration curve in the range of 0.66–35.5 μM and 0.83–35.1 μM for histidine and tryptophan, respectively. The effect of various parameters such as concentration of CdSe QDs, concentration of H2O2 and concentration of imidazole on the intensity of CL system were studied. The main experimental advantage of the proposed method is it’s selective to two amino acids compared with other amino acids.

The enhancing effect of histidine and tryptophan on chemiluminescence (CL) of CdSe quantum dots (QDs)–H2O2 system was studied. This reaction is based on the catalytic effect of amino acids, causing a significant increase in the light emission, as a result of the reaction of quantum dots (QDs) with hydrogen peroxide.Figure optionsDownload as PowerPoint slide