Copper(II) complexes with 4-hydroxyacetophenone-derived acylhydrazones: Synthesis, characterization, DNA binding and cleavage properties

New Schiff base-hydrazone ligands have led to two new copper complexes binding to the DNA through non-covalent mode and act as good metallonucleases through oxidative cleavage mechanism. The effect of complex concentration on the DNA cleavage reactions has also investigated. X-ray powder diffraction illustrates that [Cu(L2)2] complex is crystalline in nature while [Cu(H2L1)2] has an amorphous structure.