Intermolecular and low-frequency intramolecular Raman scattering study of racemic ibuprofen

• Racemic ibuprofen Raman scattering spectra was measured at room and low temperatures.
• First principle calculations of the ibubrofen molecule dynamics properties were performed.
• Correlations between the molecule and crystal vibrations were established.

We report the low-temperature Raman scattering study of racemic ibuprofen. Detailed analysis of the racemic ibuprofen crystal symmetry, related to the vibrational properties of the system, has been presented. The first principle calculations of a single ibuprofen molecule dynamical properties are compered with experimental data. Nineteen, out of 26 modes expected for the spectral region below 200 cm−1, have been observed.

Figure optionsDownload as PowerPoint slide