کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1231248 | 1495264 | 2013 | 8 صفحه PDF | دانلود رایگان |
The polyether antibiotic Lasalocid acid has been converted to its Mannich base derivative by a chemoselective one-pot reaction with formaldehyde and morpholine through the decarboxylation process. Spectroscopic studies of the structure of this new derivative have shown that in this ortho-phenol Mannich base the OH⋯N intarmolecular hydrogen bond is present. The compound forms complexes with Li+, Na+ and K+ cations of exclusively 1:1 stoichiometry. The structures of these complexes have been studied and visualized by semi-empirical calculation based on results of spectrometric and spectroscopic investigation. It is demonstrated that in contrast to Lasalocid acid the novel Mannich type derivative forms preferential complexes with Li+ cation.
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► A new ortho-phenol Mannich base of Lasalocid was synthesized by chemoselective one-pot reaction.
► The compound obtained is a useful ligand for complexation of monovalent cations.
► Spectroscopic characterization of the ligand and prepared complexes is given.
► Semiempirical calculations of structures of the complexes studied are presented.
Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy - Volume 104, March 2013, Pages 497–504