کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1254311 971368 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Two new diterpenoids from the endophytic fungus Trichoderma sp. Xy24 isolated from mangrove plant Xylocarpus granatum
ترجمه فارسی عنوان
دو نوع دیترپوئید جدید از قارچ Endophytic Trichoderma sp. Xy24 جدا شده از گیاه منجمد Xylocarpus granatum
کلمات کلیدی
هارزان دیترپنوئید؛ Trichoderma sp. Xy24؛ قارچ Endophytic؛ درختچه حرا؛ فعالیت سیتوتوکسیک
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
چکیده انگلیسی

Two new harziane diterpenoids, named (9R,10R)-dihydro-harzianone (1) and harzianelactone (2), were isolated from the endophytic fungus Trichoderma sp. Xy24 by using various column chromatography techniques. Their structures were determined on the basis of extensive spectroscopic (HR-ESI-MS, 1D NMR, 2D NMR and CD) analyses. Among them, 1 was the reductive product of harzianone and 2 was the Baeyer–Villiger monooxygenase catalyzed oxidation product of harzianone. Compound 1 exhibited cytotoxic activity against HeLa and MCF-7 cell lines with IC50 values of 30.1 μmol/L and 30.7 μmol/L, respectively.

Two new harziane diterpenoids, named (9R,10R)-dihydro-harzianone (1) and harzianelactone (2), were isolated from the endophytic fungus Trichoderma sp. Xy24. Their structures were determined on the basis of extensive spectroscopic (HR-ESI-MS, 1D NMR, 2D NMR and CD) analyses. Compound 1 exhibited cytotoxic activity against HeLa and MCF-7 cell lines.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 27, Issue 6, June 2016, Pages 957–960
نویسندگان
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