Modified gelatin with quaternary ammonium salts containing epoxide groups

An EPDDMAC-GE polymer (hydrophilic molecule) has been synthesized based on epoxypropyl dodecyl dimethyl ammonium chloride (EPDDMAC) and gelatin. A DEEPSAC-GE polymer (hydrophobic molecule) has been synthesized based on diethyl-2,3-epoxypropyl-[3-methyldimethoxyl] silpropyl ammonium chloride (DEEPSAC) and gelatin. Compared with initial gelatin, the gelatin modified with quaternary ammonium salts containing epoxide groups exhibits stronger antibacterial activity.

Two kinds of macromolecule polymers, in which EPDDMAC-GE is the hydrophilic molecules and DEEPSAC-GE is the hydrophobic molecules, have been synthesized based on the quaternary ammonium salt containing epoxide groups grafted into gelatin. Compared with initial gelatin, the gelatin modified with quaternary ammonium salts containing epoxide groups exhibits stronger antibacterial activity.Figure optionsDownload as PowerPoint slide