Synthesis of O-glycosyl α-aryl nitrones

α-Aryl nitrone are one of the most useful kinds of nitrones and have been extensively explored in recent years. However, the sugar moieties have not been introduced into these molecules before. We presented here an efficient synthesis of α-aryl nitrone O-glycosides via condensation of N-substituted hydroxylamine and aryl aldehydes glycosides in benzene.