A new polyhydroxysteroidal glycoside from the starfish Anthenea chinensis

A new polyhydroxysteroidal glycoside, (20R,24R)-16-O-(4-O-methyl-2-acetamido-2-deoxy-β-d-galactopyranosyl)-24-ethyl-5α-cholest-8(14)-en-3β,6β,7β,16α-tetrol (anthenoside A, 1), was isolated from the starfish Anthenea chinensis. Its structure was elucidated by extensive spectral analysis and chemical evidences. 1 exhibited significant cytotoxicity against human tumor K-562, BEL-7402 and U87MG cells.