کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1258096 | 971599 | 2009 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Molecular modeling of epsilon RNA from hepatitis B virus
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
An initial model of the HBV epsilon RNA was built by the Biopolymer module of Insight II. While its three-dimensional structure was obtained through structure optimization based on molecular dynamics simulation, the two active sites were found. A comparison with the experimental result indicated that the active sites may be the binding sites of the epsilon RNA in the RT-epsilon interaction. The result will be helpful to further discussion about the mechanism of RT-epsilon interaction and the study of HBV genome replication.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 20, Issue 10, October 2009, Pages 1263-1266
Journal: Chinese Chemical Letters - Volume 20, Issue 10, October 2009, Pages 1263-1266
نویسندگان
Huai Ren Pan, Hai Jun Zhu, Zhong Rong Song, Xu Dong Zhang, Huai Cao,