Oxidation of benzyl alcohols to the corresponding carbonyl compounds catalyzed by copper (II) meso-tetra phenyl porphyrin as cytochrome P-450 model reaction

The oxidation of benzyl alcohols has been studied in the presence of isobutyraldehyde as co-catalyst, molecular oxygen as oxidant and copper (II) meso-tetra phenyl porphyrin (CuTPP) as catalyst. The CuTPP catalyst exhibits good activity and high selectivity under mild conditions. The effects of temperature and solvents have also been investigated in this catalyst system.

The oxidation of benzyl alcohols has been studied in the presence of isobutyraldehyde as co-catalyst, molecular oxygen as oxidant and copper (II) meso-tetra phenyl porphyrin (CuTPP) as catalyst. The CuTPP catalyst exhibits good activity and high selectivity under mild conditions. The effects of temperature and solvents also have been investigated in this catalyst system.Figure optionsDownload as PowerPoint slideHighlights
► Homogeneous oxidation of benzyl alcohols has been done under atmospheric pressure of oxygen.
► The electronic effect of the substituents in the benzyl alcohols and reaction behavior has been compared.
► Also it was found that the yield of reaction was rather low in the absence of the catalyst.