کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1316752 | 976478 | 2006 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Oxidative DNA cleavage induced by an iron(III) flavonoid complex: Synthesis, crystal structure and characterization of chlorobis(flavonolato)(methanol) iron(III) complex
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی معدنی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A flavonol iron(III) complex, [Fe(flavonolato)2Cl(MeOH)], has been prepared. The compound has been characterized by X-ray crystallography, spectroscopy, magnetism and electronic paramagnetic resonance (EPR) at X- and Q-band. The geometrical environment around the metal is best described as rhombic distorted octahedral. This distortion has also been inferred from the magnetic measurements and from the EPR spectra at different temperatures, E/D(rhombicity parameter) ≈ 0.06. The DNA cleavage activity of the iron(III) complex with and without ascorbate/hydrogen peroxide is reported. Mechanisms of the oxidative cleavage have been proposed when DNA strand scission is performed both with and without ascorbate/hydrogen peroxide activation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Inorganic Biochemistry - Volume 100, Issue 7, July 2006, Pages 1208–1218
Journal: Journal of Inorganic Biochemistry - Volume 100, Issue 7, July 2006, Pages 1208–1218
نویسندگان
Fátima Ben Allal El Amrani, Lourdes Perelló, Jose A. Real, Marta González-Alvarez, Gloria Alzuet, Joaquín Borrás, Santiago García-Granda, José Montejo-Bernardo,