Triphenyltin chloride as a new source of phenyl group for C-heteroatom and C–C bond formation

• Ph3SnCl is introduced as a new atom economy source of phenyl group.
• Ph3SnCl is used for O-, N-, and S-arylation reactions at room temperature.
• Ph3SnCl is used for Stille reaction of aryl halides catalyzed by nano and bulk Pd(0).

Ph3SnCl is introduced as a very suitable source of phenyl group for coupling with phenols, amines, and thiols in the presence of Cu(OAc)2 in Et3N at room temperature to give aryl ethers, amines, and arylthio ethers in high yields. In addition, the application of Ph3SnCl in the Stille coupling of aryl halides in the presence of Pd(0) catalyst in PEG 400 at 110 °C is discussed.

Ph3SnCl is introduced as a very suitable source of phenyl group for coupling with phenols, amines, and thiols in the presence of Cu(OAc)2. In addition, the application of Ph3SnCl in the Stille coupling of aryl halides in the presence of PdCl2/Ph3P and PdCl2/SDPP is discussed.Figure optionsDownload as PowerPoint slide