The Heck-type arylation of allylic alcohols with arenediazonium salts

The Heck coupling of ArN2BF4 with secondary allylic alcohols, carried out in methanol using Pd(dba)2 as catalyst without extra ligands and base, leads to the corresponding β-arylated carbonyl compounds. Such conditions afford arylated acetals from primary allylic alcohols.

The Heck coupling of ArN2BF4 with allylic alcohols has been carried out in methanol using Pd(dba)2 as catalyst in the absence of extra ligand and base.Figure optionsDownload as PowerPoint slide