کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1388187 | 982773 | 2009 | 8 صفحه PDF | دانلود رایگان |
The dehydration behaviour of α,α-trehalose (α-d-glucopyranosyl α-d-glucopyranoside) dihydrate single crystals is investigated by thermomicroscopy, Raman microscopy, and differential scanning calorimetry. The results show at a given stage the simultaneous presence of two polymorphic forms, amorphous material, and movement of a fluid phase. The study also underlines that the characterization of the average phase by conventional XRPD and DSC techniques is not sufficient to describe the dehydration mechanisms of α,α-trehalose particles. Moreover, it confirms that the dehydration behaviour is mainly driven by heterogeneities and the rate of water loss.
Coexistence of three trehalose phases (TRE-h, TRE-am and TRE-β) in the same crystal at ambient temperature.Figure optionsDownload as PowerPoint slide
Journal: Carbohydrate Research - Volume 344, Issue 18, 14 December 2009, Pages 2539–2546