کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1389636 | 982904 | 2008 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The use of tri-O-acetyl-d-glucal and -d-galactal in the synthesis of ω-aminoalkyl 2-deoxy- and 2,3-dideoxy-d-hexopyranosides
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
We report a simple, efficient, and mild method for the synthesis of ω-aminoalkyl 2-deoxy-d-arabino/lyxo-hexopyranoside and 2,3-dideoxy-α-d-erythro-hexopyranoside. The total synthesis is accomplished in two sequential reactions. The first step consists of an addition reaction of N-(ω-hydroxyalkyl)phthalimide and N-(ω-hydroxyalkyl)succinimide to peracetylated d-glycals, which is promoted by triphenylphosphine hydrobromide or borontrifluoride/diethyl etherate. The second step involves reacting the appropriate glycoside with methylamine.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 343, Issue 15, 13 October 2008, Pages 2680–2686
Journal: Carbohydrate Research - Volume 343, Issue 15, 13 October 2008, Pages 2680–2686
نویسندگان
Anna W. Pierwocha, Krzysztof Walczak,