کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1643304 | 1517246 | 2015 | 4 صفحه PDF | دانلود رایگان |
• 3D nanofibrous scaffolds with controlled pore size are obtained by electrospinning.
• Pores are structured in columns which size can be tuned from 80 to 360 µm.
• Columns of pores are merging in the thickness forming a porosity gradient.
A novel strategy to prepare thick nanofibrous scaffolds with controlled pore size and graded porosity by electrospinning was developed. Taking advantage of the self-assembling properties of bimodal nanofibers, it was possible to grow columns of pores with mm height. The use of a honeycomb microstructured collector allows the control of the pore diameter from 80 to 360 µm. With increasing sample thickness, the columns of pores begin to merge creating a gradient in pore diameter of up to several hundreds of microns. These scaffolds should be ideal for tissue engineering applications.
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Journal: Materials Letters - Volume 142, 1 March 2015, Pages 180–183