کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
176015 458930 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cell internalization of BODIPY-based fluorescent dyes bearing carbohydrate residues
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Cell internalization of BODIPY-based fluorescent dyes bearing carbohydrate residues
چکیده انگلیسی


• New distyryl BODIPY derivatives have been prepared and well characterized.
• The new BODIPY dyes emit in the red region with high quantum yield.
• Their cell internalization was demonstrated by fluorescence microscopy.
• The sugar moieties seem influence cell uptake pathway.

Red-absorbing BODIPY species have been prepared and their photophysical properties have been studied. The high fluorescence quantum yield of such compounds allowed us to study their cell internalization by fluorescence microscopy, using concentration as low as nM. The results indicate that the new species are internalized within VERO cells and that the clathrin-dependent mechanism plays a crucial role in the cell internalization of the dyes.

New red-absorbing and emitting carbohydrate-containing BODIPY species are internalized within VERO cells, exhibiting negligible cytotoxicity. The clathrin-dependent mechanism plays a crucial role in the cell internalization of the BODIPY dyes.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Dyes and Pigments - Volume 110, November 2014, Pages 67–71
نویسندگان
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