کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2019078 1542166 2016 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fat type in phytosterol products influence their cholesterol-lowering potential: A systematic review and meta-analysis of RCTs
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
پیش نمایش صفحه اول مقاله
Fat type in phytosterol products influence their cholesterol-lowering potential: A systematic review and meta-analysis of RCTs
چکیده انگلیسی

The most common form of phytosterol (PS) fortified foods are fat spreads and dairy products. The predominant fats used are soybean/sunflower (SS) or rapeseed/canola (RC) oils and animal fat (D) in dairy products. This review aimed to investigate whether the carrier fat is a determinant of the hypocholesterolaemic effects of PS fortified foods. Databases were searched using relevant keywords and published RCTs from 1990 investigating the effects of dietary PS intervention (≥ 1.5 g per day) on total cholesterol and LDL-C were included. After methodological quality assessment and data extraction, a total of 32 RCTs (RC, n = 15; SS, n = 9; D, n = 8) were included. As expected, all fat groups significantly reduced TC and LDL-C (p < 0.01). When compared across different carrier fats, RC as the main carrier fat, reduced LDL-C significantly more than the SS spreads (p = 0.01). Therefore, a combination of monounsaturated fatty acid rich spread with adequate amounts of omega-3 fatty acids (as evident in RC spreads) may be the superior carrier fat for the delivery of PS for optimal blood cholesterol-lowering. The findings of this research provide useful evidence for optimising the hypocholesterolaemic effects of PS and support further investigation into the possible mechanisms behind these findings.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Lipid Research - Volume 64, October 2016, Pages 16–29
نویسندگان
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