کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2031953 1071639 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Parenteral Nutrition and preOp preparation in prevention of post-operative insulin resistance in gastrointestinal carcinoma
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی، ژنتیک و زیست شناسی مولکولی (عمومی)
پیش نمایش صفحه اول مقاله
Parenteral Nutrition and preOp preparation in prevention of post-operative insulin resistance in gastrointestinal carcinoma
چکیده انگلیسی

ABSTRACTPurposeThe aim was to compare preventive effect of total parenteral nutrition (TPN) and oral nutrition (preOp) on the perioperative insulin resistance prevention in surgical gastrointestinal cancer patients.Material/MethodsThe study was conducted in a group of 75 elective gastric and large intestine cancer patients. Patients were randomly divided into 3 study groups, 25 patients each: group I (NIL) - no preparations influencing tissue sensitivity to insulin, group II (TPN) - total parenteral nutrition in its preoperative stage and group III (TPN + preOp) parenteral nutrition and preOp in the preoperative phase.ResultsImmediately after the surgery, no statistically significant differences in insulin resistance level between groups were observed. During the first 6 postoperative hours, a statistically significant decrease of insulin resistance level in the TPN+ preOp group in comparison to others, was observed. During the first 24 postoperative hours, the NIL group was the only one to keep the insulin resistance level the same as in the preoperative phase.ConclusionsApplication of TPN in the preoperative phase leads to shortening of perioperative insulin resistance time. Combining TPN with oral application of carbohydrate before surgical procedure is an effective and the best method in postoperative insulin resistance syndrome prevention.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advances in Medical Sciences - Volume 58, Issue 1, June 2013, Pages 150–155
نویسندگان
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