کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2117297 | 1085199 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Radiothérapie exclusive curative chez un patient atteint d'un carcinome bronchique non à petites cellules de stade IV oligométastatique : cas clinique et revue de la littérature
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
SBRTRadiothérapie en conditions stéréotaxiquesCBNPCOligometastatic disease - بیماری OligometastaticAblative therapy - درمان AblativeTraitement curatif - درمان جراحیCancer bronchique non à petites cellules - سرطان ریه سلول غیر سلولیNSCLC - سرطان ریوی غیر سلول کوچکNon-small cell lung cancer - سرطان غیر سلول کوچک ریهstereotactic body radiation therapy - پرتودرمانی استریوتاکتیک بدن
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Metastatic non-small cell lung cancer is associated with a poor prognosis, and palliative chemotherapy is the mainstay of treatment. However, long-time survival has been observed in oligometastatic patients treated with locally ablative therapies to all sites of metastatic disease. An 80-year-old man was diagnosed with an adenocarcinoma of the lung. The right upper lobe lesion was classified cT2aN0M0Â and was treated with stereotactic body radiation therapy at the dose of 60Â Gy in eight fractions. A few months after, he successively presented with two brain metastases and one left adrenal metastasis, with a complete response on the primary tumor. The three secondary lesions were treated with stereotactic body radiation therapy alone. Thirty months after the diagnosis and 12Â months after metastases' apparition, primary and brain lesion kept controlled (complete response). Oligometastatic non-small cell lung cancer management is not clear. Locally ablative therapies such as stereotactic body radiation therapy, surgery and radiofrequency are efficient and should be considered. A phase III study should evaluate radical treatment strategies in such patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer/Radiothérapie - Volume 19, Issue 3, May 2015, Pages 192-197
Journal: Cancer/Radiothérapie - Volume 19, Issue 3, May 2015, Pages 192-197
نویسندگان
C. Leduc, D. Antoni, Ã. Quoix, G. Noël,