کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2538103 1559633 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Caesalpinone A, a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, from the pods of Caesalpinia spinosa Kuntze
ترجمه فارسی عنوان
Caesalpinone A، نوع جدیدی از gorgonane sesquiterpenoid حاوی 1،15-پل بی سابقه از غلاف گل ابریشم spinosa در Kuntze
کلمات کلیدی
تارا؛ spinosa در گل ابریشم؛ Sesquiterpenoid؛ Caesalpinone
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
چکیده انگلیسی


• Caesalpinone A, a gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, was isolated from Caesalpinia spinosa Kuntze
• The isodaucane and caryolane sesquiterpenoids were isolated from Caesalpinia genus for the first time.
• Compound 1 was evaluated for cytotoxic activity, but it was inactive.

Caesalpinone A (1), a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, along with ten known sesquiterpenoids (2 − 11) were isolated from the pods of Caesalpinia spinosa Kuntze (Tara). The structure of caesalpinone A was elucidated based on its 1D and 2D NMR spectra. The absolute configuration of 1 was assigned by the comparison of the experimental and calculated electronic circular dichroism spectra. Compound 1 was evaluated for the inhibitory activities against five human tumor cell lines. The sesquiterpenoids of isodaucane skeleton and caryolane skeleton were isolated from Caesalpinia genus for the first time. Compounds 5–9 were firstly reported from Tara.

Figure optionsDownload high-quality image (82 K)Download as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 112, July 2016, Pages 233–236
نویسندگان
, , , , , ,