کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2576417 1561353 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of melatonin on serum cholesterol status with formation of alpha-naphthylisothiocyanate-induced liver injury in rats
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی مولکولی
پیش نمایش صفحه اول مقاله
Effect of melatonin on serum cholesterol status with formation of alpha-naphthylisothiocyanate-induced liver injury in rats
چکیده انگلیسی

Liver injury with cholestasis appeared 24 h, but not 12 h, after treatment of rats with alpha-naphthylisotiocyanate (ANIT) (75 mg/kg, i.p.). Serum total, free, and estrified cholesterol levels were unchanged at 12 h after ANIT treatment but increases in serum total and free cholesterol levels occurred at 24 h. Melatonin (100 mg/kg, p.o.) administered at 12 h after ANIT treatment significantly attenuated these increases at 24 h after the treatment. Thus, melatonin attenuates the disruption of serum cholesterol status with liver injury formation in rats treated with ANIT.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Congress Series - Volume 1304, 1 November 2007, Pages 380–383
نویسندگان
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