Adult women with Turner syndrome: A systematic evaluation of current and past psychiatric illness, social functioning, and self-esteem

Abnormalities in both quality of life and cognitive measures have been well-documented in women with Turner Syndrome (TS). Additionally, shyness and social anxiety appear to be common clinical features of TS. However, few studies have systematically examined the presence of mood and behavior syndromes in these women. In this chapter we report our recent studies on the psychological and social aspects of Turner syndrome in adult women. Overall, rates of psychiatric syndromes were not higher in women with TS than in women attending gynecologic clinics. Nonetheless, premature ovarian failure was associated with depression, reduced self-esteem and impaired social functioning. Elucidation of the specific mechanisms of this effect and identification of the women at particular risk are important areas for further study. Attention to psychological health and social functioning should be an important part of the care for women with premature ovarian failure, regardless of the underlying disorder.