Off-label Prescriptions: how to Identify Them, Frame Them, Announce Them and Monitor Them in Practice?

This temporary and exceptional mechanism will authorize a recognized off-label prescription, which may be reimbursed and monitored for 3 years. These TURs will only concern a small portion of “off-label” drugs having yet a positive risk/benefit ratio (conditional MA) but this is far from matching with majority of off-label prescriptions. As such, and in order to improve the use of drugs, it is important to propose a control system for all “off-label” prescriptions with a dedicated committee: the “off-label” committee which would determine the frame of the “off-label” prescriptions.