کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2606510 1134207 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fever effects and treatment in critical care: Literature review
ترجمه فارسی عنوان
اثرات تب و درمان بر مراقبت های ویژه: بررسی ادبیات
کلمات کلیدی
درجه حرارت؛ تب؛ درمان تب تيروئيد؛ عفونت؛ مرگ؛ بیماران بزرگسال
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مراقبت های ویژه و مراقبتهای ویژه پزشکی
چکیده انگلیسی

Considering that the incidence of fever may reach up to 75% among critically ill adults, healthcare professionals employed in the Intensive Care Unit (ICU) are called to evaluate and manage patient temperature elevation on a daily basis. This literature review synthesizes the evidence about the effects of fever and antipyretic treatment in ICU patients. Although the febrile response acts protectively against infections, noxious effects are possible for patients with cerebral damage, neuropsychiatric disorders or limited cardiorespiratory reserve. Observational studies on ICU populations have reported associations between fever magnitude and patient mortality. Especially recent findings indicated that infected patients may significantly benefit from temperature elevation, while high fever may be maladaptive for non-infected ones. Aggressive antipyretic treatment of ICU patients has not been followed by decreased mortality in randomized trials. However, fever suppression and return to normothermia improved outcomes of septic shock patients. Antipyretic treatment should begin with drug administration and proceed with external cooling in case of refractory fever, but adverse effects of both antipyretic methods should always be considered. This article concludes by providing implications for antipyretic treatment of critically ill adults and suggesting areas for future research.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Australian Critical Care - Volume 26, Issue 3, August 2013, Pages 130–135
نویسندگان
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