کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2647528 1139047 2015 6 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
Gynecological malignancy risk in colorectal cancer survivors: A population-based cohort study
ترجمه فارسی عنوان
خطر سرطان پوستی در بازماندگان سرطان کولورکتال: یک مطالعه کوهورت مبتنی بر جمعیت
کلمات کلیدی
سرطان روده بزرگ؛ مطالعه کوهورت مجدد؛ داده های بیمه؛ سرطان پستان؛ سرطان آندومتری؛ سرطان تخمدان
Colorectal cancer; Retrospective cohort study; Insurance data; Breast cancer; Endometrial cancer; Ovarian cancer
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
چکیده انگلیسی

PurposeThis study was carried out to assess the risk of gynecological malignancy in colorectal cancer survivors using a population-based retrospective cohort study.MethodUsing the National Health Insurance Research Database (NHIRD) of Taiwan, we identified 37,176 patients with colorectal cancer diagnosed in 1998–2009, aged 20 years and above, without other cancer history. We also randomly selected 148,700 women without any cancer in the comparison cohort, frequency matched by age and diagnosis date. Incidences and hazards of breast, cervix, endometrial and ovarian cancers were evaluated by 201l.ResultsThe overall incidence of the 4 types of gynecological cancer was 39.0% higher in colorectal cancer patients than in comparisons (2.99 vs. 2.14 per 1000 person-years) with an adjusted hazard ratio (HR) of 1.46 (95% confidence interval (CI) = 1.31–1.62). Breast cancer accounted for most subsequent cancer. The multivariable Cox method measured HR was the highest for endometrial cancer (3.40, 95% CI = 2.59–4.47) for the colorectal cohort relative to comparisons, followed by ovarian cancer and breast cancer, except cervix cancer. The risk of gynecological malignancies was apparently elevated for colorectal cancer survivors <50 years of age.ConclusionsFollow-up measures are suggested for women with colorectal cancer for early detection and prevention of the subsequent gynecological malignancy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Oncology Nursing - Volume 19, Issue 5, October 2015, Pages 473–478
نویسندگان
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